For research use only.
Molecular Weight(MW): 360.83
Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative.
Selleck's Fenofibrate has been cited by 6 publications
2 Customer Reviews
E. The mTOR-lipin1-SREBP1 pathway in the liver of the Rab8af/f and Rab8a-mKO female mice gavaged with fenofibrate (25 mg/kg) or vehicle (H2O) for 8 days. F. mRNA expression of key genes in lipid metabolism in the liver of the Rab8af/f and Rab8a-mKO female mice gavaged with fenofibrate or vehicle for 8 days. n = 4-6. Statistical analyses were carried out using two-way ANOVA. * indicates p <0.05. n.s., not significant.
Diabetes, 2017, 66(9):2387-2399. Fenofibrate purchased from Selleck.
E, protein expression of ABCG1, ABCA1 and SR-B1; F, densitometric quantification of ABCG1; G, densitometric quantification of ABCA1; H, densitometric quantification of SR-B1. FB: fenofibrate; B: blank control. Data are expressed as the mean ± SD. * p < 0.05 vs. blank control group; ** p < 0.01 vs. blank control group; # p < 0.05 vs. FB group.
Food Funct, 2018, 9(12):6608-6617. Fenofibrate purchased from Selleck.
Purity & Quality Control
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|Description||Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative.|
|In vitro||DMSO||72 mg/mL (199.53 mM)|
|Ethanol||46 mg/mL (127.48 mM)|
|In vivo||Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+40% PEG 300+2% Tween 80+ddH2O
For best results, use promptly after mixing.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT03869931||Recruiting||Drug: Fenofibrate||Diabetes Mellitus|Diabetic Nephropathies||Singapore General Hospital|National Medical Research Council (NMRC) Singapore||March 8 2019||Phase 3|
|NCT03557983||Not yet recruiting||Drug: Fenofibrate|Drug: Saline||Radiodermatitis||Second Affiliated Hospital of Soochow University||June 13 2018||Not Applicable|
|NCT03515213||Active not recruiting||Drug: Fenofibrate|Drug: Placebo||Huntington Disease||University of California Irvine||April 27 2017||Phase 2|
|NCT02891408||Completed||Drug: Firsocostat|Drug: Fenofibrate||Nonalcoholic Steatohepatitis (NASH)||Gilead Sciences||September 23 2016||Phase 1|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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