Fosfomycin calcium

For research use only.

Catalog No.S3710 Synonyms: phosphomycin calcium, phosphonomycin calcium

Fosfomycin calcium Chemical Structure

CAS No. 26472-47-9

Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.

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Biological Activity

Description Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
Targets
MurA [1]
()

Protocol

References

Solubility (25°C)

In vitro DMSO 0.1 mg/mL (0.56 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 176.12
Formula

C3H5O4P.Ca

CAS No. 26472-47-9
Storage powder
in solvent
Synonyms phosphomycin calcium, phosphonomycin calcium
Smiles CC1C(O1)P(=O)([O-])[O-].[Ca+2]

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID