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Furaltadone HCl Bacterial chemical

Name: Furaltadone HCl
Brand: Selleck Chemicals
SKU: S4203
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S4203

Furaltadone HCl(Altafur hydrochloride) is an antibacterial and has distinct curative effect in the treatment of coccidiosis.

Chemical Structure

Molecular Weight: 360.75

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability Specificity

Quality Control

Batch: S420301 Water]72 mg/mL]false]DMSO]17 mg/mL]false]Ethanol]Insoluble]false Purity: 99.2%

99.2

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Chemical Information, Storage & Stability

Molecular Weight	360.75	Formula	C₁₃H₁₆N₄O₆.HCl	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	3759-92-0	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	Altafur hydrochloride			Smiles	C1COCCN1CC2CN(C(=O)O2)N=CC3=CC=C(O3)[N+](=O)[O-].Cl

Solubility

In vitro
Batch:

Water : 72 mg/mL

DMSO : 17 mg/mL (47.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro	Isoniazide as well as AOZ and 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), the latter deriving from furaltadone, cause irreversible damage to the prosthetic group of enzymes as well as degrade their polypeptide chain and cause fragmentation of the backbone chain of cellular or isolated DNA and RNA.
References	[1] https://pubmed.ncbi.nlm.nih.gov/15864325/

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