Florfenicol

Catalog No.S4201 Synonyms: SCH-25298

For research use only.

Florfenicol (SCH-25298) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.

Florfenicol Chemical Structure

CAS No. 73231-34-2

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Florfenicol (SCH-25298) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.
In vitro

Florfenicol is found to stimulate algal growth at concentrations of 0.5, 1.0 and 2.0 mg/L, and significantly inhibit algal growth at >2.0 mg/L.

In vivo Florfenicol administers at doses of 15 and 20 mg FFC kg(-1) bw per days for 10 days significantly reduces mortality associated with francisellosis in Nile tilapia.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 358.21
Formula

C12H14Cl2FNO4S

CAS No. 73231-34-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)NC(=O)C(Cl)Cl)O

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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