Fenoldopam mesylate

For research use only.

Catalog No.S4618 Synonyms: SKF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate

Fenoldopam mesylate Chemical Structure

CAS No. 67227-57-0

Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

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Biological Activity

Description Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
Targets
D1 receptor [1]
()
In vivo Fenoldopam (20 μg/kg) induced a marked decrease in systolic blood pressure, diastolic blood pressure and heart rate[1].

Protocol

Animal Research:

[1]

- Collapse
  • Animal Models: Conscious sinoaortic denervated dogs
  • Dosages: 0.9% NaCl
  • Administration: i.v.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 80 mg/mL (199.07 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 401.86
Formula

C16H16ClNO3.CH4O3S

CAS No. 67227-57-0
Storage powder
in solvent
Synonyms SKF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate
Smiles CS(=O)(=O)O.C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=C(C=C3)O

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Dopamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID