Furosemide sodium

For research use only.

Catalog No.S5194 Synonyms: Lasix, Frusemide Sodium

Furosemide sodium Chemical Structure

CAS No. 41733-55-5

Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor.

Purity & Quality Control

Choose Selective NKCC Inhibitors

Biological Activity

Description Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor.
Targets
NKCC [1]
()
GABAA receptor [2]
()

Protocol

Solubility (25°C)

In vitro DMSO 71 mg/mL (201.28 mM)
Water 71 mg/mL (201.28 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 352.73
Formula

C12H10ClN2NaO5S

CAS No. 41733-55-5
Storage powder
in solvent
Synonyms Lasix, Frusemide Sodium

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04972617 Not yet recruiting Diagnostic Test: albumin function analysis (ABIC) Acute Renal Failure|Critical Illness University of Rostock September 2021 --
NCT04331132 Not yet recruiting Drug: Tolvaptan 15 MG Acute Heart Failure Gia Dinh People Hospital|Otsuka Pharmaceutical Vietnam August 1 2021 Not Applicable
NCT04846816 Recruiting Combination Product: SQIN-01 Heart Failure SQ Innovation Inc.|University of Glasgow|NHS Greater Glasgow and Clyde May 6 2021 Phase 1
NCT04622709 Recruiting Drug: Furosemide (loop diuretic) Tablets Chronic Kidney Disease Requiring Chronic Dialysis University of North Carolina Chapel Hill|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) October 7 2020 Phase 2
NCT04556864 Not yet recruiting -- Covid19|Hemodynamic Instability|ARDS Human Juan Victor Lorente|Edwards Lifesciences|Andalusian Network for Design and Translation of Advanced Therapies October 1 2020 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field
Tags: buy Furosemide sodium | Furosemide sodium supplier | purchase Furosemide sodium | Furosemide sodium cost | Furosemide sodium manufacturer | order Furosemide sodium | Furosemide sodium distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID