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Heparin Thrombin inhibitor

Cat.No.E5835

Heparin is a highly sulfated polysaccharide primarily used as an anticoagulant, which works mainly by inhibiting thrombin (FIIa) and/or factor Xa (FXa). It is commonly used to prevent and treat thromboembolic conditions such as deep vein thrombosis and pulmonary embolism. It also plays roles in inflammation, angiogenesis, and growth factor signaling, with potential therapeutic applications in cancer treatment and allergic conditions.
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 15000-19000 Formula Storage (From the date of receipt)
CAS No. 9005-49-6 -- Storage of Stock Solutions

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Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-07-27)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06494878 RECRUITING
Venous Thromboembolism; Postpartum Period; Aspirin; Low Molecular Weight Heparin
University of Calgary
2026-06-04 PHASE3
NCT07140211 RECRUITING
Venous Thromboembolism (VTE); Postpartum
Marc Blondon
2025-10-15 PHASE3
NCT07783880 NOT_YET_RECRUITING
Myocardial Infarction; Percutaneous Coronary Intervention (PCI); Medical Treatment; Coronary Computed Tomographic Angiography; Computed Tomography; Optical Coherence Tomography (OCT)
3W-Research Collaboration Group
2026-10-01
NCT06753786 RECRUITING
Venous Thromboembolism; Pulmonary Embolism; Intracerebral Hemorrhage; Deep Vein Thrombosis
Pirogov Russian National Research Medical University
2024-10-21
NCT06381661 RECRUITING
Sepsis
Assistance Publique - Hôpitaux de Paris
2026-07-09 PHASE2
NCT06714864 RECRUITING
Catheter-Related Infections
CorMedix Therapeutics
2025-07-08 PHASE4

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