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Hydroxypropyl Cellulose

Name: Hydroxypropyl Cellulose
Brand: Selleck Chemicals
SKU: S4115
Rating: 5 (1 reviews)

Catalog No.S4115 Purity: 99%

Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility, it is used as food additive and sieving matrix for DNA separations.

Hydroxypropyl Cellulose Chemical Structure

CAS: 9004-64-2

Selleck's Hydroxypropyl Cellulose has been cited by 1 publication

Purity & Quality Control

M.W ~100000
Finest quality approved by Nature Medicine
COA
Datasheet
SDS

Hydroxypropyl Cellulose Related Products

Biological Activity

Description	Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility, it is used as food additive and sieving matrix for DNA separations.
Features	An ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CHCH3 groups.

In vitro
In vitro	Hydroxypropyl cellulose (HPC) has a relatively low viscosity, allowing for microchip channel filling to be performed with ease at concentrations as high as 5%, a MES/TRIS buffer system at pH 6.1 eliminates the need for surface preconditioning procedures due to the promotion of hydrogen bonding of HPC with the wall. ^[1] Hydroxypropyl cellulose (HPC) is used as a core molecule for controlled grafting of monomers by ATRP. Hydroxypropyl cellulose (HPC) is either allowed to react with an ATRP initiator or the first generation initiator-functionalized 2,2-bis(methylol)propionic acid dendron to create macroinitiators having high degrees of functionality. ^[2] Hydroxypropyl cellulose (HPC)/vinyl polymer networks are synthesized in film form from liquid-crystalline solutions of HPC in a mixed solvent of methacrylate monomer/methanol/water (2:1:2 in weight) containing cross-linking agents, via photopolymerization of the methacrylate monomer. The polymer composite films, HPC/PDEGMEM and HPC/PHPMA, prepared at ca. 60-70 wt % concentrations of HPC in the starting solutions, are iridescently colored due to the selective light reflection, originating from the cholesteric helical arrangement carried over successively into the network system. ^[3]

References

Chemical Information & Solubility

Molecular Weight		Formula	C₃H₈O₂.xUnspecified
CAS No.	9004-64-2	SDF	Download Hydroxypropyl Cellulose SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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