Hypericin

For research use only.

Catalog No.S3273 Synonyms: Hyp, HY

1 publication

Hypericin Chemical Structure

CAS No. 548-04-9

Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).

Selleck's Hypericin has been cited by 1 publication

Purity & Quality Control

Choose Selective MAO Inhibitors

Biological Activity

Description Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).
Targets
MAO [1]
()
PKC [1]
()
dopamine-beta-hydroxylase [1]
()
Reverse transcriptase [1]
()
Telomerase [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 100 mg/mL (198.23 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 504.44
Formula

C30H16O8

CAS No. 548-04-9
Storage powder
in solvent
Synonyms Hyp, HY

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05013567 Not yet recruiting Drug: Ibuprofen gel|Other: Placebo Musculoskeletal Pain|Acute Pain|Stretch|Sprains Brainfarma Industria Química e Farmacêutica S/A March 2022 Phase 3
NCT05031585 Not yet recruiting Device: Roncoliv|Device: Placebo Snoring|Sleep Disorder Brainfarma Industria Química e Farmacêutica S/A February 1 2022 Not Applicable
NCT04725539 Recruiting Procedure: hypoxic exposure Coronary Artery Disease (CAD) Institute of Mountain Emergency Medicine|Istituto Auxologico Italiano|University of Innsbruck|University of Giessen October 1 2021 Not Applicable
NCT04939701 Not yet recruiting Drug: ASP0739|Drug: Pembrolizumab Ovarian Cancer|NSCLC|ESCC|Solid Tumors Astellas Pharma Global Development Inc.|Astellas Pharma Inc September 30 2021 Phase 1|Phase 2
NCT04949607 Not yet recruiting Dietary Supplement: Inulin fructooligosaccharide Brain Injury Chronic|Brain Injuries Traumatic Centre for Neuro Skills|University of Texas July 1 2021 Not Applicable
NCT04837196 Recruiting Drug: ASP7517|Drug: Pembrolizumab Advanced Malignancies|Advanced Cancer Astellas Pharma Global Development Inc.|Astellas Pharma Inc July 29 2021 Phase 1|Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

MAO Signaling Pathway Map

Related MAO Products

Tags: buy Hypericin | Hypericin supplier | purchase Hypericin | Hypericin cost | Hypericin manufacturer | order Hypericin | Hypericin distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID