Home Others Others Hypromellose

research use only

Hypromellose

Cat.No.S4444

Hypromellose (Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices. This compound provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect.
Hypromellose Chemical Structure
Jump to

Quality Control

99

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight Formula Storage (From the date of receipt) 3 years -20°C powder
CAS No. 9004-65-3 -- Storage of Stock Solutions

Read more about storage stability stock solution CAS number

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-07-30)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05660447 UNKNOWN
Rhegmatogenous Retinal Detachment; Proliferative Vitreoretinopathy
Wills Eye
 2023-02-06 PHASE2; PHASE3
NCT05577910 COMPLETED
Meibomian Gland Dysfunction
Chinese University of Hong Kong
 2022-10-08
NCT05470868 COMPLETED
Hyperemia Eye
Laboratorios Sophia S.A de C.V.
 2023-02-04 PHASE1
NCT05825599 Completed
Dry Eye|Dry Eye Disease|Kerato Conjunctivitis Sicca
C.O.C. Farmaceutici S.r.l.
 2022-09-06 Not Applicable
NCT05358873 COMPLETED
SARS CoV 2 Infection; SARS-CoV-2 Acute Respiratory Disease
Chulalongkorn University
 2022-04-20
NCT04541888 COMPLETED
Dry Eye
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.
 2020-11-05 PHASE3

Read more about Clinical Trials

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.