Hyaluronidase

Synonyms: Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase

Hyaluronidase (Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase) is a naturally occurring enzyme that degrades hyaluronic acid, which constitutes an essential part of the extracellular matrix. It depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been utilized in ophthalmic surgery.

Hyaluronidase Chemical Structure

Hyaluronidase Chemical Structure

CAS: 37326-33-3 (9004-54-1)

Selleck's Hyaluronidase has been cited by 1 publication

Purity & Quality Control

Batch: S442401 Water] 100 mg/mL] false] DMSO] Insoluble] false] Ethanol] Insoluble] false Purity: 99%
99

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Biological Activity

Description Hyaluronidase (Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase) is a naturally occurring enzyme that degrades hyaluronic acid, which constitutes an essential part of the extracellular matrix. It depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been utilized in ophthalmic surgery.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04578535 Completed
Healthy Volunteers
Baxalta now part of Shire|Baxalta Innovations GmbH now part of Shire|Takeda
October 27 2020 Phase 1

Chemical Information & Solubility

Molecular Weight Formula

C17H24BrNO2

CAS No. 37326-33-3 (9004-54-1) SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
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In vivo Formulation Calculator

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

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