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Hyaluronic acid (Hyaluronan)

Cat.No.S5865

Hyaluronic acid (Hyaluronan) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is widely used in skin care.
Hyaluronic acid (Hyaluronan) Chemical Structure

Chemical Structure

Molecular Weight: 200000~400000

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Chemical Information, Storage & Stability

Molecular Weight 200000~400000 Formula Storage (From the date of receipt) 3 years -20°C powder
CAS No. 9004-61-9 -- Storage of Stock Solutions

Solubility

In vitro
Batch:

Water : 5 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06325696 Not yet recruiting
Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis|Lung Diseases Interstitial
National Institute of Environmental Health Sciences (NIEHS)|National Institutes of Health Clinical Center (CC)
 May 15 2024 Phase 2
NCT06243744 Recruiting
Skin Laxity|Tissue Degeneration|Tissue Breakdown|Collagen Degeneration|Collagen Shrinkage
Apyx Medical
 November 30 2023 Not Applicable
NCT06050837 Not yet recruiting
High Risk Esophageal Varices
Institute of Liver and Biliary Sciences India
 September 30 2023 --
NCT05295680 Recruiting
Primary Sclerosing Cholangitis
Aparna Goel|Stanford University
 May 10 2023 Phase 2

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