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Antibiotics
Antibiotics Products
- All (206)
- Antibiotics Inhibitors (30)
- New Antibiotics Products
| Catalog No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| S1208 | Doxorubicin (DOX) HCl | Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease. |
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| S7417 | Puromycin 2HCl | Puromycin 2HCl is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinated expression of genes during cell differentiation. | ||
| S7046 | Brefeldin A (BFA) | Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy. |
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| S1228 | Idarubicin HCl | Idarubicin HCl (4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL in a cell-free assay. Idarubicin induces mTOR-dependent cytotoxic autophagy. |
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| S5159 | Doxycycline | Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor. | ||
| S4226 | Minocycline HCl | Minocycline HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. | ||
| S3028 | Geneticin (G418 Sulfate) | Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.It is commonly used as a screening reagent for eukaryotic cells to screen transfected or transformed cells. | ||
| S1373 | Daptomycin | Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms. |
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| S1408 | Linezolid (PNU-100766) | Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections. |
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| S1835 | Azithromycin | Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections. | ||
| S7419 | Blasticidin S HCl | Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes. It acts by blocking hydrolysis of peptidyl-tRNA induced by release factors and inhibits peptide bond formation. It is used to select transfected cells carrying bsr or BSD resistance genes. | ||
| S6068 | Doxycycline monohydrate | Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. | ||
| S1636 | Amphotericin B | Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes. | ||
| E2894 | Penicillin-Streptomycin | Penicillin-Streptomycin is used to prevent microbial contamination of cell culture during long-term in vitro cell culture maintenance. 100× solution stabilized with 10,000 units penicillin and 10 milligrams streptomycin per milliliter, suitable for cell culture applications. | ||
| S2527 | Methacycline HCl | Methacycline HCl (Rondomycin) is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections. | ||
| S2908 | Hygromycin B | Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome. | ||
| S1741 | Rifabutin (LM427) | Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis. | ||
| S1450 | Nanchangmycin | Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants. | ||
| S3015 | Amoxicillin | Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. | ||
| S5535 | Moxifloxacin | Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro. | ||
| S5784 | Vancomycin | Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria. | ||
| S1399 | Teicoplanin | Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria. | ||
| S1502 | Cephalexin | Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections. | ||
| S1635 | Erythromycin | Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml). | ||
| S2565 | Amoxicillin Sodium | Amoxicillin Sodium (Clavulanate,Amoxycillin sodium) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic. | ||
| S2574 | Tetracycline HCl | Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic. | ||
| S4056 | Retapamulin | Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM. | ||
| S1505 | Aztreonam | Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection. | ||
| S4030 | Gentamicin Sulfate | Gentamycin Sulfate (NSC-82261, SCH9724) is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.Gentamicin Sulfate can be used to induce animal models of Renal Failure. | ||
| S4848 | Dalbavancin | Dalbavancin is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci. | ||
| S2152 | Sitafloxacin Hydrate | Sitafloxacin Hydrate (DU-6859a) is a new-generation, broad-spectrum oral fluoroquinolone antibiotic. | ||
| S1773 | Oxytetracycline (Terramycin) | Oxytetracycline(Terramycin) is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria. |
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| S2506 | Roxithromycin | Roxithromycin (Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin,RU-28965) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. | ||
| S4093 | Bismuth Subcitrate Potassium | Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection. | ||
| S3122 | Amikacin hydrate | Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections. | ||
| S5531 | Doripenem | Doripenem(S 4661) is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens. | ||
| S3971 | Fusidine | Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis. | ||
| S4148 | Ampicillin Trihydrate | Ampicillin Trihydrate (NCI-C56086,D-(-)-α-Aminobenzylpenicillin trihydrate) is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. | ||
| S4158 | Ceftriaxone disodium salt hemi (heptahydrate) | Ceftriaxone disodium salt hemi (heptahydrate) is a third-generation cephalosporin antibiotic. | ||
| S4160 | Penicillin G Sodium | Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp. | ||
| S5298 | Amoxicillin trihydrate | Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. | ||
| S4720 | Cefotaxime | Cefotaxime(HR-756) is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria. | ||
| S4215 | Ribostamycin Sulfate | Ribostamycin Sulfate(Vistamycin Sulfate,Landamycine) is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidificus. | ||
| S4222 | Piperacillin Sodium | Piperacillin (CL227193,Pipracil) is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. | ||
| S5206 | Benzylpenicillin potassium | Benzylpenicillin potassium (Penicillin G potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. | ||
| S4783 | Benzyl isothiocyanate | Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities. | ||
| S3170 | Ampicillin sodium | Ampicillin(D-(-)-α-Aminobenzylpenicillin sodium salt) is a beta-lactam antibiotic that is part of the aminopenicillin family. | ||
| S4279 | Demeclocycline HCl | Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections. | ||
| S1374 | Doripenem Hydrate | Doripenem Hydrate (S-4661) is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections. | ||
| S2510 | Spectinomycin 2HCl | Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis. | ||
| S2568 | Neomycin sulfate | Neomycin sulfate(Framycin sulfate) is an aminoglycoside antibiotic, used to treat bacteria infections. | ||
| S4052 | Netilmicin Sulfate | Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics. | ||
| S4082 | Spiramycin | Spiramycin (Formacidine) is a 16-membered ring macrolide (antibiotic). | ||
| S2514 | Tobramycin | Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM. | ||
| S2539 | Lomefloxacin HCl | Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic. | ||
| S3105 | Nadifloxacin | Nadifloxacin (OPC-7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris. | ||
| S4234 | Capreomycin Sulfate | Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit. | ||
| S5051 | Pipemidic acid | Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative bacteria including Pseudomonas aeruginosa and some gram-positive bacteria. Pipemidic acid is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA. It can be used for the research of intestinal, urinary, and biliary tract infections. | ||
| S5328 | Gamithromycin | Gamithromycin (ML-1709460) is a new macrolide antibiotic that is only registered for use in cattle to treat respiratory disorders such as bovine respiratory disease. | ||
| S5199 | Oxytetracycline hydrochloride | Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | ||
| S4490 | Tetracycline | Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. | ||
| S5533 | Tobramycin sulfate | Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity. | ||
| S5008 | Ciprofloxacin (CPX) hydrochloride | Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases). | ||
| S2052 | Oxytetracycline Dihydrate | Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | ||
| S3496 | Lefamulin acetate (Xenleta) | Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer. | ||
| S6549 | PBTZ169 | PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1. | ||
| S1395 | Polymyxin B sulphate | Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections. | ||
| S4641 | Tedizolid Phosphate | Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid. | ||
| S4183 | Paromomycin Sulfate | Paromomycin Sulfate(Aminosidine sulfate) is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA. | ||
| S5330 | Amikacin Sulfate Salt | Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains. | ||
| S2315 | Kanamycin sulfate | Kanamycin sulfate (Kanamycin monosulfate, Ophtalmokalixan) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. | ||
| S6423 | Tildipirosin | Tildipirosin is a 16-membered ring, tribasic and semi-synthetic macrolide antibiotic. | ||
| S5410 | Chloramphenicol sodium succinate | Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity. | ||
| S5208 | Ciprofloxacin hydrochloride hydrate | Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox,Bay-09867 hydrochloride hydrate) is the hydrochloride salt form of ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections. | ||
| S4536 | Nitrofurantoin | Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis. | ||
| S1381 | Meropenem | Meropenem (SM 7338) is an ultra-broad spectrum injectable antibiotic. | ||
| S1370 | Biapenem | Biapenem (L-627, LJC10627) is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains. | ||
| S1371 | Cefoselis Sulfate | Cefoselis (FK 037 Sulfate) is a widely used beta-lactam antibiotic. | ||
| S2159 | Tebipenem Pivoxil | Tebipenem pivoxil (L-084, ME1211,TBPM-PI,LJC 11036) is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections. | ||
| S1768 | Cefditoren Pivoxil | Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria. | ||
| S1998 | D-Cycloserine | D-cycloserine (RO-1-9213) is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis. | ||
| S1605 | Cefdinir | Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body. | ||
| S1611 | Cefoperazone | Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM. | ||
| S1777 | Ethionamide | Ethionamide (Bayer 5312) is an antibiotic used in the treatment of tuberculosis. | ||
| S2544 | Cefprozil hydrate | Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin. | ||
| S2563 | Oxacillin sodium monohydrate | Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class. | ||
| S3129 | Trimethoprim | Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections. | ||
| S1499 | Cefaclor monohydrate | Cefaclor monohydrate(Cefachlor, Cefaclorum) is a cephalosporin antibiotic. | ||
| S1915 | Sulfamethoxazole | Sulfamethoxazole(Ro 4-2130) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM. | ||
| S1791 | Bacitracin Zinc | Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM. | ||
| S2530 | 7-Aminocephalosporanic acid | 7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates. | ||
| S2543 | Ceftiofur HCl | Ceftiofur HCl (U-67279A,Excenel hydrochloride) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection. | ||
| S3162 | Tylosin tartrate | Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry. | ||
| S1770 | Sulfadiazine | Sulfadiazine is a sulfonamide antibiotic. | ||
| S2048 | Clindamycin Phosphate | Clindamycin Phosphate (NSC 618653) is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. | ||
| S3055 | Besifloxacin HCl | Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic. | ||
| S3059 | Enrofloxacin | Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic. | ||
| S1977 | Sarafloxacin HCl | Sarafloxacin HCl (A-56620) is a hydrochloride salt form of sarafloxacin which is a quinolone antibiotic drug with IC50 of 0.96 μg/L. | ||
| S4254 | Apramycin Sulfate | Apramycin Sulfate (Ai3-29795) is an aminoglycoside antibiotic, which binds to the deep groove of the RNA. | ||
| S3179 | Carbenicillin disodium | Carbenicillin (BRL-2064,α-carboxybenzylpenicillin) is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity. | ||
| S3193 | Ticarcillin sodium | Ticarcillin (AB 2288, BRL 2288) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. | ||
| S5227 | Erythromycin thiocyanate | Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. | ||
| S5560 | Midecamycin | Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis. | ||
| E6075New | Penicillin G benzathine tetrahydrate | Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is a long-acting beta-lactam antibiotic effective against many bacterial infections such as impetigo. | ||
| S5048 | Fosfomycin Disodium | Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis. | ||
| S5353 | Cefpiramide sodium | Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients. | ||
| S5951 | Cefoxitin | Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. | ||
| S4974 | Oxacillin sodium | Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia. | ||
| S5035 | 6-Aminopenicillanic acid | 6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin. | ||
| S2583 | Thiamphenicol | Thiamphenicol (Thiophenicol,Dextrosulphenidol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol. | ||
| E8298New | Duocarmycin SA | Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA and can be used in research treatment for glioblastoma multiforme (GBM). | ||
| S4850 | Flucloxacillin sodium | Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections. | ||
| S4594 | Cephalothin sodium | Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. | ||
| S4865 | Cefetamet pivoxil hydrochloride | Cefetamet pivoxil hydrochloride is the hydrochloride salt form of cefetamet pivoxil, which is an oral third-generation cephalosporin antibiotic. | ||
| S5941 | Besifloxacin | Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. | ||
| S5268 | Solithromycin | Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor. | ||
| S4979 | Procaine penicillin G | Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic. | ||
| E4802 | Ticarcillin disodium | Ticarcillin disodium is a semisynthetic β-lactam antibiotic, which is active against Pseudomonas aeruginosa, Escherichia coli, Pseudomonas mirabilis, Pseudomonas rettgeri, and Klebsiella aerogenes. | ||
| S5278 | Tedizolid | Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria. | ||
| S4122 | Tilmicosin | Tilmicosin (EL 870,LY-177370) is a macrolide antibiotic. | ||
| S4869 | Sulfamethoxazole sodium | Sulfamethoxazole sodium is an antibiotic used for bacterial infections. | ||
| S5719 | Ceftizoxime sodium | Ceftizoxime sodium(SKF-88373) is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. | ||
| S5207 | Cephalexin Monohydrate | Cephalexin is a semisynthetic cephalosporin antibiotic with antimicrobial activity. | ||
| S4585 | Succinylsulfathiazole | Succinylsulfathiazole (Succinylsulphathiazole), a sulfonamide, is an antibiotic. | ||
| S5491 | Lomefloxacin | Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections. | ||
| S8418 | Phleomycin D1 | Phleomycin D1(PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. It causes cell death by binding and cleaving DNA. It shows antiproliferative activities and strong cytotoxicity against HT-29 cells. | ||
| S4941 | Farnesol | Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects. | ||
| S4595 | Cefazolin Sodium | Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine. | ||
| S5333 | Sulbenicillin Sodium | Sulbenicillin Sodium (Sulfocillin, Sulfobenzylpenicillin) is the sodium salt of sulbenicillin, which is a penicillin antibiotic. | ||
| S5936 | Cefazolin | Cefazolin(Cephazolin) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine. | ||
| S4596 | Cefixime | Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin. | ||
| S4150 | Orbifloxacin | Orbifloxacin(CP-104354) is a synthetic broad-spectrum fluoroquinolone antibiotic. | ||
| S7784 | Fumagillin | Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. | ||
| S4421 | Josamycin | Josamycin (EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5) is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens. | ||
| S4885 | Taurolidine | Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities. | ||
| S5968 | Kasugamycin hydrochloride hydrate | Kasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. | ||
| S4156 | Chlortetracycline HCl (NSC 13252) | Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) is the first identified tetracycline antibiotic. | ||
| S4647 | Cefmenoxime hydrochloride | Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly. | ||
| S5296 | Cephradine monohydrate | Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. | ||
| S5290 | Ormetoprim | Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture. | ||
| S5487 | Cefoperazone sodium | Cefoperazone Sodium(CP 52640-2) is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity. | ||
| S5294 | Cephalotin acid | Cephalotin acid (Cephalothin, Cefalotin, Cephalothinum) is a cephalosporin antibiotic. | ||
| S5736 | Benzathine penicilline | Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections. | ||
| S4612 | Dapson | Dapson (Dapsone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, 4-Aminophenyl sulfone, Bis(4-aminophenyl) sulfone, DDS), also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. | ||
| S1884 | Sparfloxacin | Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity. | ||
| S2385 | Hordenine | Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. | ||
| S5601 | Balofloxacin Dihydrate | Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic. | ||
| S5417 | Spectinomycin dihydrochloride pentahydrate | Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome. | ||
| S3645 | Kitasamycin | Kitasamycin (Leucomycin) is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens. | ||
| S6562 | KKL-35 | KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity. | ||
| E4877New | Lefamulin | Lefamulin (BC-3781), is a pleuromutilin antibiotic, inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. It is effective against a range of gram-positive pathogens involved in community-acquired bacterial pneumonia (CABP), including Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Legionella pneumophila, Chlamydophila pneumoniae, Staphylococcus aureus (including methicillin-resistant and vancomycin-intermediate strains), and vancomycin-resistant Enterococcus faecium. | ||
| S4179 | Mezlocillin Sodium | Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. | ||
| S4060 | Erythromycin Ethylsuccinate | Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis. | ||
| S5515 | Penicillin G Procaine | Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections. | ||
| E4996New | Puromycin | Puromycin (CL13900, Puromycine) is an antibiotic, analog of the 3' end of aminoacyl-tRNA and an inhibitor of protein synthesis that mimics tyrosyl-tRNA, causing premature termination of translation. It blocks translation by labeling and releasing elongating polypeptide chains from ribosomes and has been widely used in molecular biology research. | ||
| S5637 | Cefotiam Hexetil Hydrochloride | Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. | ||
| S5299 | Tosufloxacin p-Toluenesulfonate Hydrate | Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that is used to treat susceptible infections. | ||
| S5644 | Ceftriaxone Sodium | Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. | ||
| S5295 | Lincomycin Hydrochloride Monohydrate | Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections. | ||
| S8871 | Omadacycline tosylate | Omadacycline tosylate(PTK 0796 tosylate,Amadacycline tosylate) is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria. | ||
| S5420 | Clindamycin alcoholate | Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits. | ||
| E4906New | Cefadroxil | Cefadroxil(BL-S 578) is a first-generation, cephalosporin antibiotic with broad spectrum of anti-bacterial activity. It can be used in the management of infections in the respiratory tract, urinary tract, skin and soft tissues, and bones and joints. | ||
| S5421 | Fluoroquinolonic Acid | Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent. | ||
| S4750 | Sulfacetamide sodium salt hydrate | Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. | ||
| S6584 | Amdinocillin | Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. | ||
| S6582 | Ozenoxacin | Ozenoxacin(T-3912) is a quinolone antibiotic used for the treatment of impetigo. | ||
| S4870 | Cefodizime Sodium | Cefodizime Sodium, a third generation cephalosporin antibiotic, has broad-spectrum activity and is stable to most beta-lactamases. | ||
| S3636 | Cefadroxil hydrate | Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. | ||
| E2890 | CHIR-090 | CHIR-090 is a potent and tight-binding inhibitor of the LpxC deacetylase. It also binds to E. coli LpxC with a Ki of 4.0 nM. | ||
| S4978 | Azathramycin | Azathramycin (Azaerythromycin A, Azaerythromycin) is a macrolide antibiotic containing cladinose. | ||
| S3708 | Sulfachloropyridazine | Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections. | ||
| S4663 | Fusidate Sodium | Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections. | ||
| S5041 | Difloxacin hydrochloride | Difloxacin is a second-generation, synthetic fluoroquinolone antimicrobial antibiotic used in veterinary medicine. | ||
| S5657 | Ertapenem sodium | Ertapenem Sodium (MK826) is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass. | ||
| S4986 | Latamoxef sodium | Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects. | ||
| S4271 | Isepamicin Sulphate | Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit. | ||
| S3672 | Cefonicid sodium | Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism. | ||
| S4213 | Dirithromycin | Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides. | ||
| S4671 | Cefradine | Cefradine (Cephradine, Sefril, Anspor, Velosef) is a semi-synthetic cephalosporin antibiotic. | ||
| S5070 | Mupirocin calcium | Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic. | ||
| E6061New | Cefamandole sodium | Cefamandole (sodium) is a parenteral, broad-spectrum, second-generation cephalosporin antibiotic effective against various gram-positive and gram-negative bacteria, including Neisseria, Haemophilus, and Proteus species. | ||
| S3650 | Penicillin V potassium salt | Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan. | ||
| E4847New | Tosufloxacin | Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin effectively targets a broad spectrum of antibacterial activity, including both gram-positive and gram-negative strains. | ||
| E8174New | Streptomycin | Streptomycin (Agrept, Agrimycin, Streptomycin A) is an aminoglycoside antibiotic isolated from Streptomyces griseus and used in tuberculosis (TB) research due to its activity against Mycobacterium tuberculosis. It is also a bactericidal agent useful for studying various bacterial infections. | ||
| E6052New | Enrofloxacin hydrochloride | Enrofloxacin hydrochloride is a fluoroquinolone antibiotic with potent activity against Mycoplasma bovis, showing an MIC₉₀ of 0.312 μg/mL. It can be used in research to study treatments for pneumonia, mastitis, arthritis, and other conditions in cattle. | ||
| E0706 | Gemifloxacin mesylate | Gemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes. | ||
| E0656 | 7-Methylcoumarin | 7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity. | ||
| S4517 | Cefotaxime sodium | Cefotaxime sodium(HR-756) salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria. | ||
| S5573 | Tilmicosin phosphate | Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease. | ||
| S4523 | Dihydrostreptomycin sulfate | Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin. | ||
| S5473 | Pivmecillinam hydrochloride | Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections. | ||
| S4833 | Cefoxitin sodium | Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. | ||
| S5350 | Cefpodoxime proxetil | Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. | ||
| S4540 | Sisomicin sulfate | Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora. | ||
| E7524New | G-418 | G-418 (Geneticin, Antibiotic G-418) is an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea. It functions by binding to the ribosomal subunit, thereby inhibiting translational elongation and disrupting protein synthesis in both prokaryotic and eukaryotic cells, thus impairing cell growth and viability. | ||
| S4425 | Rifamycin S | Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. | ||
| S5744 | Spiramycin I | Spiramycin I (Foromacidin A) is a main component of spiramycin, which is a macrolide antimicrobial agent with broad spectrum antibiotic activity. | ||
| S4813 | Cefuroxime axetil | Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms. | ||
| S4436 | Pleuromutilin | Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. | ||
| S4393 | Cephapirin Sodium | Cephapirin Sodium (Cefapirin) is the sodium salt form of cephapirin, a semi-synthetic, first-generation cephalosporin antibiotic with bactericidal activity.Cephapirin Sodium is effective against gram-negative and gram-positive organisms. | ||
| S5351 | Cefmetazole sodium | Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. | ||
| S5859 | Sancycline | Sancycline (Bonomycin, Norcycline, GS 2147) is a semi-synthetic tetracycline antibiotic. | ||
| S4812 | Ceftizoxime | Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. | ||
| S4488 | Delafloxacin Meglumine | Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens. | ||
| S5108 | Tylosin | Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock. | ||
| S4847 | Faropenem Sodium | Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia. | ||
| S7417 | Puromycin 2HCl | Puromycin 2HCl is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinated expression of genes during cell differentiation. | ||
| S7046 | Brefeldin A (BFA) | Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy. |
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| S1228 | Idarubicin HCl | Idarubicin HCl (4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL in a cell-free assay. Idarubicin induces mTOR-dependent cytotoxic autophagy. |
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| S3028 | Geneticin (G418 Sulfate) | Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.It is commonly used as a screening reagent for eukaryotic cells to screen transfected or transformed cells. | ||
| S7419 | Blasticidin S HCl | Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes. It acts by blocking hydrolysis of peptidyl-tRNA induced by release factors and inhibits peptide bond formation. It is used to select transfected cells carrying bsr or BSD resistance genes. | ||
| E2894 | Penicillin-Streptomycin | Penicillin-Streptomycin is used to prevent microbial contamination of cell culture during long-term in vitro cell culture maintenance. 100× solution stabilized with 10,000 units penicillin and 10 milligrams streptomycin per milliliter, suitable for cell culture applications. | ||
| S2527 | Methacycline HCl | Methacycline HCl (Rondomycin) is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections. | ||
| S2908 | Hygromycin B | Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome. | ||
| S4783 | Benzyl isothiocyanate | Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities. | ||
| S5199 | Oxytetracycline hydrochloride | Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | ||
| S4490 | Tetracycline | Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. | ||
| S5008 | Ciprofloxacin (CPX) hydrochloride | Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases). | ||
| S3496 | Lefamulin acetate (Xenleta) | Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer. | ||
| S6549 | PBTZ169 | PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1. | ||
| S1611 | Cefoperazone | Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM. | ||
| S1791 | Bacitracin Zinc | Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM. | ||
| S4974 | Oxacillin sodium | Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia. | ||
| E8298New | Duocarmycin SA | Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA and can be used in research treatment for glioblastoma multiforme (GBM). | ||
| S4979 | Procaine penicillin G | Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic. | ||
| S4941 | Farnesol | Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects. | ||
| S7784 | Fumagillin | Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. | ||
| S4647 | Cefmenoxime hydrochloride | Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly. | ||
| E4996New | Puromycin | Puromycin (CL13900, Puromycine) is an antibiotic, analog of the 3' end of aminoacyl-tRNA and an inhibitor of protein synthesis that mimics tyrosyl-tRNA, causing premature termination of translation. It blocks translation by labeling and releasing elongating polypeptide chains from ribosomes and has been widely used in molecular biology research. | ||
| S6584 | Amdinocillin | Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. | ||
| E2890 | CHIR-090 | CHIR-090 is a potent and tight-binding inhibitor of the LpxC deacetylase. It also binds to E. coli LpxC with a Ki of 4.0 nM. | ||
| E0656 | 7-Methylcoumarin | 7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity. | ||
| E7524New | G-418 | G-418 (Geneticin, Antibiotic G-418) is an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea. It functions by binding to the ribosomal subunit, thereby inhibiting translational elongation and disrupting protein synthesis in both prokaryotic and eukaryotic cells, thus impairing cell growth and viability. | ||
| S4425 | Rifamycin S | Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. | ||
| S4436 | Pleuromutilin | Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. | ||
| S4488 | Delafloxacin Meglumine | Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens. | ||
| E6075New | Penicillin G benzathine tetrahydrate | Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is a long-acting beta-lactam antibiotic effective against many bacterial infections such as impetigo. | ||
| E8298New | Duocarmycin SA | Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA and can be used in research treatment for glioblastoma multiforme (GBM). | ||
| E4877New | Lefamulin | Lefamulin (BC-3781), is a pleuromutilin antibiotic, inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. It is effective against a range of gram-positive pathogens involved in community-acquired bacterial pneumonia (CABP), including Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Legionella pneumophila, Chlamydophila pneumoniae, Staphylococcus aureus (including methicillin-resistant and vancomycin-intermediate strains), and vancomycin-resistant Enterococcus faecium. | ||
| E4996New | Puromycin | Puromycin (CL13900, Puromycine) is an antibiotic, analog of the 3' end of aminoacyl-tRNA and an inhibitor of protein synthesis that mimics tyrosyl-tRNA, causing premature termination of translation. It blocks translation by labeling and releasing elongating polypeptide chains from ribosomes and has been widely used in molecular biology research. | ||
| E4906New | Cefadroxil | Cefadroxil(BL-S 578) is a first-generation, cephalosporin antibiotic with broad spectrum of anti-bacterial activity. It can be used in the management of infections in the respiratory tract, urinary tract, skin and soft tissues, and bones and joints. | ||
| E6061New | Cefamandole sodium | Cefamandole (sodium) is a parenteral, broad-spectrum, second-generation cephalosporin antibiotic effective against various gram-positive and gram-negative bacteria, including Neisseria, Haemophilus, and Proteus species. | ||
| E4847New | Tosufloxacin | Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin effectively targets a broad spectrum of antibacterial activity, including both gram-positive and gram-negative strains. | ||
| E8174New | Streptomycin | Streptomycin (Agrept, Agrimycin, Streptomycin A) is an aminoglycoside antibiotic isolated from Streptomyces griseus and used in tuberculosis (TB) research due to its activity against Mycobacterium tuberculosis. It is also a bactericidal agent useful for studying various bacterial infections. | ||
| E6052New | Enrofloxacin hydrochloride | Enrofloxacin hydrochloride is a fluoroquinolone antibiotic with potent activity against Mycoplasma bovis, showing an MIC₉₀ of 0.312 μg/mL. It can be used in research to study treatments for pneumonia, mastitis, arthritis, and other conditions in cattle. | ||
| E7524New | G-418 | G-418 (Geneticin, Antibiotic G-418) is an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea. It functions by binding to the ribosomal subunit, thereby inhibiting translational elongation and disrupting protein synthesis in both prokaryotic and eukaryotic cells, thus impairing cell growth and viability. |
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