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Catalog No.	Product Name	Information	Product Use Citations
E0656^New	7-Methylcoumarin	7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity.
S1228	Idarubicin HCl	Idarubicin HCl (4-demethoxydaunorubicin, NSC256439, 4-DMDR) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL in a cell-free assay. Idarubicin induces mTOR-dependent cytotoxic autophagy.	Hum Cell, 2022, 10.1007/s13577-022-00671-y Cancers (Basel), 2021, 13(14)3586 Biomolecules, 2021, 11(8)1128
S1611	Cefoperazone	Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [³H]E₂17βG uptake with IC50 of 199 μM.
S1791	Bacitracin Zinc	Bacitracin is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
S2527	Methacycline HCl	Methacycline HCl (Rondomycin) is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.	Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 10.1007/s13577-021-00639-4 Hum Cell, 2021, 34(6):1911-1918
S2908	Hygromycin B	Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.	Autophagy, 2021, 1-17 PLoS Pathog, 2021, 17(4):e1009530 Cell Res, 2020,
S3028	Geneticin (G418 Sulfate)	Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.	Breast Cancer Res Treat, 2022, 10.1007/s10549-021-06433-y Cell Cycle, 2022, 1-17 Sci Adv, 2021, 7(7)eabd2645
S3496	Lefamulin acetate (Xenleta)	Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.	J Biol Chem, 2022, 298(5):101909
S4425	Rifamycin S	Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S4436	Pleuromutilin	Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
S4488	Delafloxacin Meglumine	Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens.
S4490	Tetracycline	Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.
S4647	Cefmenoxime hydrochloride	Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S4783	Benzyl isothiocyanate	Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.	Biomolecules, 2019, 9(12)
S4941	Farnesol	Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.
S4974	Oxacillin sodium	Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia.
S4979	Procaine penicillin G	Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.
S5008	Ciprofloxacin hydrochloride	Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
S5199	Oxytetracycline hydrochloride	Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.	Front Microbiol, 2016, 7:1765
S6549	PBTZ169	PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.	Cell Death Dis, 2019, 10(4):319
S6584	Amdinocillin	Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.
S7046	Brefeldin A	Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.	Nat Cell Biol, 2022, 24(5):766-782 Cell Mol Immunol, 2022, 10.1038/s41423-022-00841-w PLoS One, 2022, 17(3):e0265805
S7417	Puromycin (CL13900) 2HCl	Puromycin 2HCl (CL13900) is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.	Signal Transduct Target Ther, 2022, 7(1):97 Nat Commun, 2022, 13(1):478 J Hematol Oncol, 2022, 15(1):30
S7419	Blasticidin S HCl	Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor, used to select transfected cells carrying bsr or BSD resistance genes.	Nat Commun, 2022, 13(1):478 Cancer Commun (Lond), 2022, 10.1002/cac2.12311 Theranostics, 2021, 11(6):2966-2986
S7784	Fumagillin	Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
E0706^New	Gemifloxacin mesylate	Gemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes.
S1208	Doxorubicin (Adriamycin) HCl	Doxorubicin (Adriamycin, NSC 123127, DOX, Hydroxydaunorubicin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.	Adv Sci (Weinh), 2022, e2103332 Nat Chem Biol, 2022, 10.1038/s41589-022-00996-7 Bioact Mater, 2022, 18:459-470
S1370	Biapenem	Biapenem (L-627, LJC10627) is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.
S1371	Cefoselis Sulfate	Cefoselis (FK 037) is a widely used beta-lactam antibiotic.
S1373	Daptomycin (LY146032)	Daptomycin (LY146032) is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.	Comput Struct Biotechnol J, 2022, 20:2442-2454 J Phys Chem B, 2021, 125(22):5775-5785 Sci Adv, 2020, 6(34):eaba8968
S1374	Doripenem Hydrate	Doripenem Hydrate (S-4661) is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.	ACS Chem Biol, 2018, 13(8):2020-2026
S1381	Meropenem	Meropenem (SM 7338) is an ultra-broad spectrum injectable antibiotic.
S1395	Polymyxin B sulphate	Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.	Free Radic Biol Med, 2019, 137:24-36
S1399	Teicoplanin	Teicoplanin (Teichomycin) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.	ACS Appl Mater Interfaces, 2020, 12(14):16150-16158 Clin Exp Dent Res, 2016, 2(1):35-43
S1408	Linezolid (PNU-100766)	Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections.	Front Microbiol, 2020, 11:265 J Mol Cell Biol, 2019, pii: mjz020 PLoS One, 2019, 14(10):e0222970
S1450	Nanchangmycin	Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants.	Elife, 2022, 11e74513 Antimicrob Agents Chemother, 2020, 1;AAC.00289-20 Sci Rep, 2019, 9(1):1144
S1499	Cefaclor	Cefaclor (Cefachlor, Cefaclorum) is a cephalosporin antibiotic.
S1502	Cephalexin	Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections.	Clin Cancer Res, 2018, 24(3):659-673 Theranostics, 2017, 7(7):2092-2107 Blood Cancer J, 2017, 10.1038/bcj.2017.61
S1505	Aztreonam	Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.	PLoS Pathog, 2016, 12(10):e1005932 Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1605	Cefdinir	Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.
S1635	Erythromycin	Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).	J Med Chem, 2018, 61(9):4189-4202 Oncotarget, 2018, 9(40):26086-26095
S1636	Amphotericin B	Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.	Stem Cell Res Ther, 2021, 12(1):485 ACS Omega, 2021, 6(12):8477-8487 Nat Microbiol, 2020, 10.1038/s41564-020-00790-y
S1741	Rifabutin (LM427)	Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.	Antibiotics (Basel), 2020, 9(2) Antimicrob Agents Chemother, 2020, AAC.00363-20
S1768	Cefditoren Pivoxil	Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.
S1770	Sulfadiazine	Sulfadiazine is a sulfonamide antibiotic.
S1773	Oxytetracycline (Terramycin)	Oxytetracycline is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765
S1777	Ethionamide	Ethionamide (Bayer 5312) is an antibiotic used in the treatment of tuberculosis.
S1835	Azithromycin (CP-62993)	Azithromycin (CP-62993, XZ-450) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.	J Cell Biochem, 2022, 10.1002/jcb.30213 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 34(6):1911-1918
S1884	Sparfloxacin	Sparfloxacin (AT-4140, CI-978, PD 131501) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
S1915	Sulfamethoxazole	Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.
S1977	Sarafloxacin HCl	Sarafloxacin HCl (A-56620) is a hydrochloride salt form of sarafloxacin which is a quinolone antibiotic drug with IC50 of 0.96 μg/L.
S1998	D-Cycloserine	D-cycloserine (RO-1-9213) is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis.
S2048	Clindamycin Phosphate	Clindamycin Phosphate (NSC 618653) is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.
S2052	Oxytetracycline Dihydrate	Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.	Front Microbiol, 2016, 7:1765
S2152	Sitafloxacin Hydrate	Sitafloxacin Hydrate (DU-6859a) is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.	Interact Cardiovasc Thorac Surg, 2018, 10.1093/icvts/ivy209 mSphere, 2018, 3(5)
S2159	Tebipenem Pivoxil	Tebipenem pivoxil (L-084, ME1211) is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.
S2315	Kanamycin sulfate	Kanamycin sulfate (Kanamycin monosulfate, Ophtalmokalixan) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.	Oncotarget, 2018, 9(40):26086-26095
S2385	Hordenine	Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
S2506	Roxithromycin	Roxithromycin (Roxl-150) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.	Chemistry, 2020, 10.1002/chem.201905599 J Med Chem, 2018, 61(9):4189-4202
S2510	Spectinomycin 2HCl	Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis.	Cell Rep, 2020, 32(2):107897
S2514	Tobramycin	Tobramycin (NSC 180514) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.	Oncotarget, 2018, 9(40):26086-26095
S2530	7-Aminocephalosporanic acid	7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.
S2539	Lomefloxacin HCl	Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.	Front Microbiol, 2020, 10:2936
S2543	Ceftiofur HCl	Ceftiofur HCl (U-67279A) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.
S2544	Cefprozil hydrate	Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.
S2563	Oxacillin sodium monohydrate	Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
S2565	Amoxicillin Sodium	Amoxicillin Sodium (Clavulanate) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489 Toxicol Appl Pharmacol, 2015, 285(1):51-60
S2568	Neomycin sulfate	Neomycin sulfate is an aminoglycoside antibiotic, used to treat bacteria infections.	Mol Cell, 2020, 22 pii: S1097-2765(20)30231-8
S2574	Tetracycline HCl	Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.	PLoS Pathog, 2020, 16;16(3):e1008341 Antiviral Res, 2020, 185:104993 Sci Rep, 2018, 8(1):7653
S2583	Thiamphenicol	Thiamphenicol (Thiophenicol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.
S3015	Amoxicillin	Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489 Toxicol Appl Pharmacol, 2015, 285(1):51-60
S3055	Besifloxacin HCl	Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.
S3059	Enrofloxacin	Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.
S3105	Nadifloxacin	Nadifloxacin (OPC-7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.	Pharmaceutics, 2021, 13(8)1289
S3122	Amikacin hydrate	Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections.	Molecules, 2019, 25(1)
S3129	Trimethoprim	Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
S3162	Tylosin tartrate	Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.
S3170	Ampicillin sodium	Ampicillin is a beta-lactam antibiotic that is part of the aminopenicillin family.	Exp Ther Med, 2022, 23(3):216 Vet J, 2018, 234:24-26
S3179	Carbenicillin disodium	Carbenicillin (BRL-2064) is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
S3193	Ticarcillin sodium	Ticarcillin (AB 2288, BRL 2288) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
S3636	Cefadroxil hydrate	Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
S3645	Kitasamycin	Kitasamycin (Leucomycin) is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens.
S3650	Penicillin V potassium salt	Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
S3672	Cefonicid sodium	Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
S3708	Sulfachloropyridazine	Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections.
S3971	Fusidine	Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
S4030	Gentamicin Sulfate	Gentamycin Sulfate (NSC-82261, SCH9724) is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.	Universitätsmedizin Berlin, 2021, 10.17169/refubium-29871 Cell, 2020, S0092-8674(20)31394-5
S4052	Netilmicin Sulfate	Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.	J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S4056	Retapamulin	Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with K_d of 3 nM.	Pediatr Infect Dis J, 2021, 40(7):637-638 Hum Mol Genet, 2020, ddaa244
S4060	Erythromycin Ethylsuccinate	Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
S4082	Spiramycin	Spiramycin (Formacidine) is a 16-membered ring macrolide (antibiotic).	Chemistry, 2020, 10.1002/chem.201905599
S4093	Bismuth Subcitrate Potassium	Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.	Cell Rep, 2022, 38(6):110359 J Clin Invest, 2020, 130(7):3901-3918
S4122	Tilmicosin	Tilmicosin (EL 870) is a macrolide antibiotic.
S4148	Ampicillin Trihydrate	Ampicillin Trihydrate (NCI-C56086) is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.	Bone Joint Res, 2020, 16;9(4):152-161
S4150	Orbifloxacin	Orbifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic.
S4156	Chlortetracycline HCl (NSC 13252)	Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) is the first identified tetracycline antibiotic.
S4158	Ceftriaxone disodium salt hemi (heptahydrate)	Ceftriaxone disodium salt hemi (heptahydrate) is a third-generation cephalosporin antibiotic.	J Neurochem, 2020, 155(4):370-389 J Neurochem, 2020, 155(4):370-389
S4160	Penicillin G Sodium	Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.	Cell Rep, 2015, 11(1):98-110
S4179	Mezlocillin Sodium	Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.
S4183	Paromomycin Sulfate	Paromomycin Sulfate is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.
S4213	Dirithromycin	Dirithromycin (LY-237216, ASE 136) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.
S4215	Ribostamycin Sulfate	Ribostamycin (Vistamycin) is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidiﬁcus.	PLoS Pathog, 2020, 16;16(3):e1008341 Pathogens, 2019, 8(3)
S4222	Piperacillin Sodium	Piperacillin (CL227193) is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.	Cancer Discov, 2020, CD-20-0160 Analytical Methods, 2018, 10.1039/C8AY00150B
S4226	Minocycline (CL 59806) HCl	Minocycline (CL 59806) HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.	Int J Mol Sci, 2022, 23(5)2793 Front Bioeng Biotechnol, 2022, 10:855755 Neuropharmacology, 2022, 207:108950
S4234	Capreomycin Sulfate	Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.	Mol Cell Proteomics, 2019, 18(2):231-244
S4254	Apramycin Sulfate	Apramycin Sulfate (Ai3-29795) is an aminoglycoside antibiotic, which binds to the deep groove of the RNA.
S4271	Isepamicin Sulphate	Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.
S4279	Demeclocycline HCl	Demeclocycline HCl is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.	J Biol Chem, 2020, 10.1074/jbc.RA119.011633. Sci Rep, 2018, 8(1):7653
S4393	Cephapirin Sodium	Cephapirin Sodium (Cefapirin) is the sodium salt form of cephapirin, a semi-synthetic, first-generation cephalosporin antibiotic with bactericidal activity.Cephapirin Sodium is effective against gram-negative and gram-positive organisms.
S4421	Josamycin	Josamycin (EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5) is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
S4517	Cefotaxime sodium	Cefotaxime sodium salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.
S4523	Dihydrostreptomycin sulfate	Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin.
S4536	Nitrofurantoin	Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.
S4540	Sisomicin sulfate	Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora.
S4585	Succinylsulfathiazole	Succinylsulfathiazole (Succinylsulphathiazole), a sulfonamide, is an antibiotic.
S4594	Cephalothin sodium	Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
S4595	Cefazolin Sodium	Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
S4596	Cefixime	Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.
S4612	Dapson	Dapson (Dapsone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, 4-Aminophenyl sulfone, Bis(4-aminophenyl) sulfone, DDS), also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.
S4641	Tedizolid Phosphate	Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.	Sci Transl Med, 2019, 11(516)
S4663	Fusidate Sodium	Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
S4671	Cefradine	Cefradine (Cephradine, Sefril, Anspor, Velosef) is a semi-synthetic cephalosporin antibiotic.
S4720	Cefotaxime	Cefotaxime is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria.
S4750	Sulfacetamide sodium salt hydrate	Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.
S4812	Ceftizoxime	Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
S4813	Cefuroxime axetil	Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
S4833	Cefoxitin sodium	Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S4847	Faropenem Sodium	Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
S4848	Dalbavancin	Dalbavancin (Zeven, BI 397, MDL 63397) is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci.
S4850	Flucloxacillin sodium	Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S4865	Cefetamet pivoxil hydrochloride	Cefetamet pivoxil hydrochloride is the hydrochloride salt form of cefetamet pivoxil, which is an oral third-generation cephalosporin antibiotic.
S4869	Sulfamethoxazole sodium	Sulfamethoxazole sodium is an antibiotic used for bacterial infections.
S4870	Cefodizime Sodium	Cefodizime Sodium, a third generation cephalosporin antibiotic, has broad-spectrum activity and is stable to most beta-lactamases.
S4885	Taurolidine	Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.
S4978	Azathramycin	Azathramycin (Azaerythromycin A, Azaerythromycin) is a macrolide antibiotic containing cladinose.
S4986	Latamoxef sodium	Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.
S5035	6-Aminopenicillanic acid	6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin.
S5041	Difloxacin hydrochloride	Difloxacin is a second-generation, synthetic fluoroquinolone antimicrobial antibiotic used in veterinary medicine.
S5048	Fosfomycin Disodium	Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
S5051	Pipemidic acid	Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative and some gram-positive bacteria.	Hum Mol Genet, 2020, ddaa244
S5070	Mupirocin calcium	Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.
S5108	Tylosin	Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.
S5159	Doxycycline	Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.	Mol Cancer, 2022, 21(1):43 Mol Cell, 2022, S1097-2765(22)00433-6 Theranostics, 2022, 12(7):3131-3149
S5206	Benzylpenicillin potassium	Benzylpenicillin potassium (Penicillin G potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic.
S5207	Cephalexin Monohydrate	Cephalexin is a semisynthetic cephalosporin antibiotic with antimicrobial activity.
S5208	Ciprofloxacin hydrochloride hydrate	Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox) is the hydrochloride salt form of ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections.
S5227	Erythromycin thiocyanate	Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
S5268	Solithromycin	Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S5278	Tedizolid (TR-700)	Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
S5290	Ormetoprim	Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture.
S5294	Cephalotin acid	Cephalotin acid (Cephalothin, Cefalotin, Cephalothinum) is a cephalosporin antibiotic.
S5295	Lincomycin Hydrochloride Monohydrate	Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
S5296	Cephradine monohydrate	Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
S5298	Amoxicillin trihydrate	Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489
S5299	Tosufloxacin p-Toluenesulfonate Hydrate	Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that is used to treat susceptible infections.
S5328	Gamithromycin	Gamithromycin (ML-1709460) is a new macrolide antibiotic that is only registered for use in cattle to treat respiratory disorders such as bovine respiratory disease.	Hum Cell, 2020, 10.1007/s13577-020-00420-z
S5330	Amikacin Sulfate Salt	Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains.
S5333	Sulbenicillin Sodium	Sulbenicillin Sodium (Sulfocillin, Sulfobenzylpenicillin) is the sodium salt of sulbenicillin, which is a penicillin antibiotic.
S5350	Cefpodoxime proxetil	Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
S5351	Cefmetazole sodium	Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
S5353	Cefpiramide sodium	Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
S5410	Chloramphenicol sodium succinate	Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.	Oncotarget, 2018, 9(40):26086-26095
S5417	Spectinomycin dihydrochloride pentahydrate	Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome.
S5420	Clindamycin alcoholate	Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S5421	Fluoroquinolonic Acid	Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent.
S5473	Pivmecillinam hydrochloride	Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
S5487	Cefoperazone sodium	Cefoperazone Sodium is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
S5491	Lomefloxacin	Lomefloxacin is a fluoroquinolone antibiotic used to treat bacterial infections.
S5515	Penicillin G Procaine	Procaine benzylpenicillin (Procaine benzylpenicillin), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
S5531	Doripenem	Doripenem is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens.	Biomed Chromatogr, 2017, 31(5)
S5533	Tobramycin sulfate	Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.	Oncotarget, 2018, 9(40):26086-26095
S5535	Moxifloxacin	Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.	Transl Vis Sci Technol, 2018, 7(2):11 J Pharmacol Toxicol Methods, 2017, 90:39-47 Circ Arrhythm Electrophysiol, 2016, 9(4):e003655
S5560	Midecamycin	Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S5573	Tilmicosin phosphate	Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease.
S5601	Balofloxacin Dihydrate	Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic.
S5637	Cefotiam Hexetil Hydrochloride	Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
S5644	Ceftriaxone Sodium	Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.
S5657	Ertapenem sodium	Ertapenem Sodium (MK826) is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass.
S5719	Ceftizoxime sodium	Ceftizoxime sodium is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
S5736	Benzathine penicilline	Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
S5744	Spiramycin I	Spiramycin I (Foromacidin A) is a main component of spiramycin, which is a macrolide antimicrobial agent with broad spectrum antibiotic activity.
S5784	Vancomycin	Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria.	Gut Microbes, 2020, 12(1):1-20 Oncotarget, 2018, 9(40):26086-26095
S5859	Sancycline	Sancycline (Bonomycin, Norcycline, GS 2147) is a semi-synthetic tetracycline antibiotic.
S5936	Cefazolin	Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
S5941	Besifloxacin	Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis.
S5951	Cefoxitin	Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S5968	Kasugamycin hydrochloride hydrate	Kasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs.
S6068	Doxycycline monohydrate	Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity.	Mol Cancer, 2022, 21(1):43 Theranostics, 2022, 12(7):3131-3149 EMBO Rep, 2022, e52984
S6423	Tildipirosin	Tildipirosin is a 16-membered ring, tribasic and semi-synthetic macrolide antibiotic.	Nat Cell Biol, 2017, 19(10):1274-1285
S6562	KKL-35	KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity.
S6582	Ozenoxacin	Ozenoxacin is a quinolone antibiotic used for the treatment of impetigo.
S8871	Omadacycline tosylate	Omadacycline tosylate is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria.
E0656^New	7-Methylcoumarin	7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity.
S1228	Idarubicin HCl	Idarubicin HCl (4-demethoxydaunorubicin, NSC256439, 4-DMDR) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL in a cell-free assay. Idarubicin induces mTOR-dependent cytotoxic autophagy.	Hum Cell, 2022, 10.1007/s13577-022-00671-y Cancers (Basel), 2021, 13(14)3586 Biomolecules, 2021, 11(8)1128
S1611	Cefoperazone	Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [³H]E₂17βG uptake with IC50 of 199 μM.
S1791	Bacitracin Zinc	Bacitracin is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
S2527	Methacycline HCl	Methacycline HCl (Rondomycin) is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.	Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 10.1007/s13577-021-00639-4 Hum Cell, 2021, 34(6):1911-1918
S2908	Hygromycin B	Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.	Autophagy, 2021, 1-17 PLoS Pathog, 2021, 17(4):e1009530 Cell Res, 2020,
S3028	Geneticin (G418 Sulfate)	Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.	Breast Cancer Res Treat, 2022, 10.1007/s10549-021-06433-y Cell Cycle, 2022, 1-17 Sci Adv, 2021, 7(7)eabd2645
S3496	Lefamulin acetate (Xenleta)	Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.	J Biol Chem, 2022, 298(5):101909
S4425	Rifamycin S	Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S4436	Pleuromutilin	Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
S4488	Delafloxacin Meglumine	Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens.
S4490	Tetracycline	Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.
S4647	Cefmenoxime hydrochloride	Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S4783	Benzyl isothiocyanate	Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.	Biomolecules, 2019, 9(12)
S4941	Farnesol	Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.
S4974	Oxacillin sodium	Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia.
S4979	Procaine penicillin G	Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.
S5008	Ciprofloxacin hydrochloride	Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
S5199	Oxytetracycline hydrochloride	Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.	Front Microbiol, 2016, 7:1765
S6549	PBTZ169	PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.	Cell Death Dis, 2019, 10(4):319
S6584	Amdinocillin	Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.
S7046	Brefeldin A	Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.	Nat Cell Biol, 2022, 24(5):766-782 Cell Mol Immunol, 2022, 10.1038/s41423-022-00841-w PLoS One, 2022, 17(3):e0265805
S7417	Puromycin (CL13900) 2HCl	Puromycin 2HCl (CL13900) is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.	Signal Transduct Target Ther, 2022, 7(1):97 Nat Commun, 2022, 13(1):478 J Hematol Oncol, 2022, 15(1):30
S7419	Blasticidin S HCl	Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor, used to select transfected cells carrying bsr or BSD resistance genes.	Nat Commun, 2022, 13(1):478 Cancer Commun (Lond), 2022, 10.1002/cac2.12311 Theranostics, 2021, 11(6):2966-2986
S7784	Fumagillin	Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
E0656^New	7-Methylcoumarin	7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity.
E0706^New	Gemifloxacin mesylate	Gemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes.