Cephalothin

For research use only.

Catalog No.S4594 Synonyms: Cefalotin

Cephalothin Chemical Structure

Molecular Weight(MW): 418.42

Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.

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Biological Activity

Description Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.

Protocol

References

Solubility (25°C)

In vitro Water 83 mg/mL (198.36 mM)
DMSO 10 mg/mL (23.89 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 418.42
Formula

C16H15N2NaO6S2

CAS No. 58-71-9
Storage powder
in solvent
Synonyms Cefalotin
Smiles [Na+].CC(=O)OCC1=C(N2C(SC1)C(NC(=O)CC3=CC=CS3)C2=O)C([O-])=O

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID