Polymyxin B sulphate

Catalog No.S1395 Synonyms: Aerosporin, PMB, Poly-RX

For research use only.

Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.

Polymyxin B sulphate Chemical Structure

CAS No. 1405-20-5

Selleck's Polymyxin B sulphate has been cited by 1 Publication

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 1301.56
Formula

C56H98N16O13.H2SO4

CAS No. 1405-20-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01795872 Completed Procedure: Several diagnostic procedures Multiple Sclerosis Bayer September 2013 Phase 4
NCT00951353 Completed -- Chronic Kidney Failure|End Stage Renal Disease National Institute of Allergy and Infectious Diseases (NIAID) July 2009 --

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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