Cefonicid sodium

For research use only.

Catalog No.S3672 Synonyms: Monocid sodium

Cefonicid sodium Chemical Structure

CAS No. 61270-78-8

Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
In vivo The intravenous administration of cefonicid or cefazedone to beagle dogs causes a dose-dependent incidence of anemia, neutropenia, and thrombocytopenia after 1-3 months of treatment. Administration of high doses of cefonicid to dogs can induce hematotoxicity similar to the cephalosporin-induced blood dyscrasias[1].

Protocol

Animal Research:[1]
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  • Animal Models: beagle dogs
  • Dosages: 400-500 mg/kg
  • Administration: i.v.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (170.49 mM)
Water 100 mg/mL (170.49 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 586.53
Formula

C18H16N6O8S3.2Na

CAS No. 61270-78-8
Storage powder
in solvent
Synonyms Monocid sodium
Smiles C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)O)C(=O)[O-])CSC4=NN=NN4CS(=O)(=O)[O-].[Na+].[Na+]

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

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Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID