Nanchangmycin

For research use only.

Catalog No.S1450

4 publications

Nanchangmycin Chemical Structure

CAS No. 65101-87-3

Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants.

Size Price Stock Quantity  
10mM (1mL in DMSO) GBP 491 In stock
GBP 139 In stock
GBP 277 In stock
GBP 1384 In stock

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Selleck's Nanchangmycin has been cited by 4 publications

Purity & Quality Control

Choose Selective Anti-infection Inhibitors

Biological Activity

Description Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants.
Features Polyether antibiotic produced by Streptomyces nanchangensis NS3226.
In vitro

Nanchangmycin inhibits gram-positive bacteria. [1]

In vivo Nanchangmycin can be used as a growth promotant in poultry and to cure coccidiosis in chickens[1]. Nanchangmycin is a bacterially-derived natural product that potently blocked ZIKV infection across diverse cell types. It blocks ZIKV entry, as well as DENV infection[2].

Protocol

Cell Research:

[2]

- Collapse
  • Cell lines: U2OS
  • Concentrations: 0.7 μM
  • Incubation Time: 1 h
  • Method:

    5000 cells were plated in 25ul media per well in 384-well plates. The next day, 50 nl of drugs were transfered to each well for a final concentration of 0.7uM/0.2% DMSO in U2OS. The drug treated U2OS cells were infected with Zika MR766, MOI=0.125 and fixed at 48 hours post infection (hpi).


    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (112.47 mM)
Ethanol 100 mg/mL (112.47 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 889.1
Formula

C48H80O13

CAS No. 65101-87-3
Storage powder
in solvent
Synonyms N/A
Smiles CC1CC(C(OC1C2CC(C3(O2)C(C(CC(O3)C4(CCC5(O4)CC(C(C(O5)C(C)C=C(C)C(=O)C(C)CC(C)C(=O)[O-])C)O)C)OC6CCC(C(O6)C)OC)C)C)(CO)O)C.[Na+]

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field
Tags: buy Nanchangmycin | Nanchangmycin supplier | purchase Nanchangmycin | Nanchangmycin cost | Nanchangmycin manufacturer | order Nanchangmycin | Nanchangmycin distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID