Cefoxitin
For research use only.
Catalog No.S5951
CAS No. 35607-66-0
Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
Purity & Quality Control
Choose Selective Anti-infection Inhibitors
Biological Activity
| Description | Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. |
|---|
Protocol
References
Solubility (25°C)
| In vitro | DMSO | 85 mg/mL (198.85 mM) |
|---|---|---|
| Ethanol | 85 mg/mL (198.85 mM) | |
| Water | Insoluble |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 427.45 |
|---|---|
| Formula | C16H17N3O7S2 |
| CAS No. | 35607-66-0 |
| Storage |
powder in solvent |
| Synonyms | N/A |
| Smiles | COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)O)NC(=O)CC3=CC=CS3 |
In vivo Formulation Calculator (Clear solution)
| Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment) | ||||||||||
| Dosage | mg/kg |  |
Average weight of animals | g | |
Dosing volume per animal | ul | |
Number of animals | |
| Step 2: Enter the in vivo formulation () | ||||||||||
| % DMSO % % Tween 80 % ddH2O | ||||||||||
| CalculateReset | ||||||||||
Calculation results:
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Bio Calculators
Molarity Calculator
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Dilution Calculator
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT03306290 | Completed | Drug: Serum dosage of antibiotic prophylaxis CEFOXITIN | Obese|Antibiotic Prophylaxis|Bariatric Surgery Candidate | Central Hospital Nancy France | October 30 2017 | Not Applicable |
| NCT03269994 | Recruiting | Drug: Cefoxitin|Drug: Piperacillin-tazobactam | Pancreatic Cancer|Pancreas Cancer|Pancreatic Diseases | Memorial Sloan Kettering Cancer Center|Indiana University|Massachusetts General Hospital|Thomas Jefferson University|Washington University School of Medicine|Advocate Illinois Masonic Medical Center|Baptist Memorial Health Care Corporation|Baylor Scott and White Health|The Cleveland Clinic|Emory University|Fox Chase Cancer Center|Gundersen Lutheran Medical Center|Hackensack Meridian Health|Hamilton Health Sciences Center|Intermountain Health Care Inc.|Jersey Shore Medical Center (Hackensack Meridian)|Johns Hopkins University|Montefiore Medical Center/Albert Einstein College of Medicine|North Shore University HealthSystem|Milton S. Hershey Medical Center|Rhode Island Hospital|Stony Brook Medicine|Sunnybrook Health Sciences Centre Canada|Temple University|The Ohio State University Wexner Medical Center|The Ottowa Hospital/University of Ottowa|University of California Davis|University of Chicago|University of Iowa|University of Texas Southwestern Medical Center|University of Utah|University of Wisconsin Madison|Providence Health & Services|Albany Medical College|Northwestern University|Universtiy of Mississippi Medical Center|Mount Sinai Hospital New York|Brody School of Medicine at East Carolina University | August 28 2017 | Phase 3 |
| NCT02703857 | Completed | Drug: cefoxitin | Antibiotic Prophylaxis Surgery | Poitiers University Hospital | February 2016 | Phase 4 |
| NCT01820793 | Terminated | Drug: Cefoxitin | Acute Pyelonephritis Without Severity Symptoms Due to ESBL-producing E.Coli | Assistance Publique - Hôpitaux de Paris | May 2013 | Not Applicable |
| NCT00752908 | Completed | -- | Obesity | Washington University School of Medicine | February 2008 | -- |
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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