Name: Cefoxitin
Brand: Selleck Chemicals
SKU: S5951
Availability: InStock
Rating: 5 (1 reviews)

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Quality Control

Batch: Purity: 99.96%

99.96

Related Targets	Integrase Antibiotics Anti-infection Fungal Antiviral COVID-19 Parasite Reverse Transcriptase HIV HCV Protease
Other Bacterial Inhibitors	Berberine BTZ043 Racemate Teicoplanin Pefloxacin Mesylate Furagin Ornidazole Proanthocyanidins Solithromycin Skatole Berberine Sulfate

Solubility

In vitro
Batch:

DMSO : 85 mg/mL (198.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	4.000mg/ml (9.36mM)	Taking the 1 mL working solution as an example, add 50 μL of 80 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.200mg/ml (0.47mM)	Taking the 1 mL working solution as an example, add 50 μL of 4 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	427.45	Formula	C₁₆H₁₇N₃O₇S₂	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	35607-66-0	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	N/A			Smiles	COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)O)NC(=O)CC3=CC=CS3

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT04775238	Unknown status	Nosocomial Infections	Sohag University	February 27 2021	Not Applicable
NCT03269994	Active not recruiting	Pancreatic Cancer\|Pancreas Cancer\|Pancreatic Diseases	Memorial Sloan Kettering Cancer Center\|Indiana University\|Massachusetts General Hospital\|Thomas Jefferson University\|Washington University School of Medicine\|Advocate Illinois Masonic Medical Center\|Baptist Memorial Health Care Corporation\|Baylor Scott and White Health\|The Cleveland Clinic\|Emory University\|Fox Chase Cancer Center\|Gundersen Lutheran Medical Center\|Hackensack Meridian Health\|Hamilton Health Sciences Center\|Intermountain Health Care Inc.\|Jersey Shore Medical Center (Hackensack Meridian)\|Johns Hopkins University\|Montefiore Medical Center/Albert Einstein College of Medicine\|North Shore University HealthSystem\|Milton S. Hershey Medical Center\|Rhode Island Hospital\|Stony Brook Medicine\|Sunnybrook Health Sciences Centre Canada\|Temple University\|The Ohio State University Wexner Medical Center\|The Ottowa Hospital/University of Ottowa\|University of California Davis\|University of Chicago\|University of Iowa\|University of Texas Southwestern Medical Center\|University of Utah\|University of Wisconsin Madison\|Providence Health & Services\|Albany Medical College\|Northwestern University\|Universtiy of Mississippi Medical Center\|Mount Sinai Hospital New York\|Brody School of Medicine at East Carolina University	November 21 2017	Phase 3
NCT03306290	Completed	Obese\|Antibiotic Prophylaxis\|Bariatric Surgery Candidate	Central Hospital Nancy France	October 30 2017	Not Applicable
NCT02703857	Completed	Antibiotic Prophylaxis Surgery	Poitiers University Hospital	February 2016	Phase 4

Tech Support

Handling Instructions

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Cefoxitin Bacterial chemical

Chemical Structure

Molecular Weight: 427.45