Cefoxitin

Catalog No.S5951

For research use only.

Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.

Cefoxitin Chemical Structure

CAS No. 35607-66-0

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 427.45
Formula

C16H17N3O7S2

CAS No. 35607-66-0
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)O)NC(=O)CC3=CC=CS3

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04775238 Recruiting Other: Silver nanoparticles|Other: Copper nanoparticles Nosocomial Infections Sohag University February 27 2021 Not Applicable
NCT03269994 Active not recruiting Drug: Cefoxitin|Drug: Piperacillin-tazobactam Pancreatic Cancer|Pancreas Cancer|Pancreatic Diseases Memorial Sloan Kettering Cancer Center|Indiana University|Massachusetts General Hospital|Thomas Jefferson University|Washington University School of Medicine|Advocate Illinois Masonic Medical Center|Baptist Memorial Health Care Corporation|Baylor Scott and White Health|The Cleveland Clinic|Emory University|Fox Chase Cancer Center|Gundersen Lutheran Medical Center|Hackensack Meridian Health|Hamilton Health Sciences Center|Intermountain Health Care Inc.|Jersey Shore Medical Center (Hackensack Meridian)|Johns Hopkins University|Montefiore Medical Center/Albert Einstein College of Medicine|North Shore University HealthSystem|Milton S. Hershey Medical Center|Rhode Island Hospital|Stony Brook Medicine|Sunnybrook Health Sciences Centre Canada|Temple University|The Ohio State University Wexner Medical Center|The Ottowa Hospital/University of Ottowa|University of California Davis|University of Chicago|University of Iowa|University of Texas Southwestern Medical Center|University of Utah|University of Wisconsin Madison|Providence Health & Services|Albany Medical College|Northwestern University|Universtiy of Mississippi Medical Center|Mount Sinai Hospital New York|Brody School of Medicine at East Carolina University November 21 2017 Phase 3
NCT03306290 Completed Drug: Serum dosage of antibiotic prophylaxis CEFOXITIN Obese|Antibiotic Prophylaxis|Bariatric Surgery Candidate Central Hospital Nancy France October 30 2017 Not Applicable
NCT02703857 Completed Drug: cefoxitin Antibiotic Prophylaxis Surgery Poitiers University Hospital February 2016 Phase 4
NCT01820793 Terminated Drug: Cefoxitin Acute Pyelonephritis Without Severity Symptoms Due to ESBL-producing E.Coli Assistance Publique - Hôpitaux de Paris May 2013 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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