Cefoxitin

Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.

Cefoxitin Chemical Structure

Cefoxitin Chemical Structure

CAS: 35607-66-0

Purity & Quality Control

Batch: Purity: 99.96%
99.96

Cefoxitin Related Products

Choose Selective Bacterial Inhibitors

Biological Activity

Description Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04775238 Unknown status
Nosocomial Infections
Sohag University
February 27 2021 Not Applicable
NCT03269994 Active not recruiting
Pancreatic Cancer|Pancreas Cancer|Pancreatic Diseases
Memorial Sloan Kettering Cancer Center|Indiana University|Massachusetts General Hospital|Thomas Jefferson University|Washington University School of Medicine|Advocate Illinois Masonic Medical Center|Baptist Memorial Health Care Corporation|Baylor Scott and White Health|The Cleveland Clinic|Emory University|Fox Chase Cancer Center|Gundersen Lutheran Medical Center|Hackensack Meridian Health|Hamilton Health Sciences Center|Intermountain Health Care Inc.|Jersey Shore Medical Center (Hackensack Meridian)|Johns Hopkins University|Montefiore Medical Center/Albert Einstein College of Medicine|North Shore University HealthSystem|Milton S. Hershey Medical Center|Rhode Island Hospital|Stony Brook Medicine|Sunnybrook Health Sciences Centre Canada|Temple University|The Ohio State University Wexner Medical Center|The Ottowa Hospital/University of Ottowa|University of California Davis|University of Chicago|University of Iowa|University of Texas Southwestern Medical Center|University of Utah|University of Wisconsin Madison|Providence Health & Services|Albany Medical College|Northwestern University|Universtiy of Mississippi Medical Center|Mount Sinai Hospital New York|Brody School of Medicine at East Carolina University
November 21 2017 Phase 3
NCT03306290 Completed
Obese|Antibiotic Prophylaxis|Bariatric Surgery Candidate
Central Hospital Nancy France
October 30 2017 Not Applicable
NCT02703857 Completed
Antibiotic Prophylaxis Surgery
Poitiers University Hospital
February 2016 Phase 4
NCT01820793 Terminated
Acute Pyelonephritis Without Severity Symptoms Due to ESBL-producing E.Coli
Assistance Publique - Hôpitaux de Paris
May 2013 Not Applicable

Chemical Information & Solubility

Molecular Weight 427.45 Formula

C16H17N3O7S2

CAS No. 35607-66-0 SDF --
Smiles COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)O)NC(=O)CC3=CC=CS3
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 85 mg/mL ( (198.85 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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