Home Microbiology Antibiotics for Mammalian Cell Culture inhibitor Penicillin G Sodium

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Penicillin G Sodium Antibiotics for Mammalian Cell Culture inhibitor

Cat.No.S4160

Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.
Penicillin G Sodium Antibiotics for Mammalian Cell Culture inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 356.37

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Quality Control

Batch: S416001 DMSO]71 mg/mL]false]Water]71 mg/mL]false]Ethanol]1 mg/mL]false Purity: 98.77%
98.77

Solubility

In vitro
Batch:

DMSO : 71 mg/mL (199.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 71 mg/mL

Ethanol : 1 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 356.37 Formula

C16H18N2O4S.Na

 Storage (From the date of receipt)
CAS No. 69-57-8 Download SDF Storage of Stock Solutions

Synonyms Benzylpenicillin Sodium Smiles CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[Na+]

Mechanism of Action

In vitro
Benzylpenicillin is also commonly known as penicillin G. Benzylpenicillin exhibits activity mainly against Gram-positive organisms. Some Gram-negative organisms such as Neisseria gonorrhoeae and Neisseria meningitidis are also reported to be susceptible to Penicillin G.

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06391125 Not yet recruiting
Syphilis Infection|Benzathine Penicillin Adverse Reaction
Washington University School of Medicine
 June 2024 Phase 3
NCT04647331 Recruiting
Infective Endocarditis
Uppsala University
 June 1 2021 --
NCT03612557 Completed
Healthy
Pfizer
 August 20 2018 Phase 1

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