research use only

Penicillin G Procaine Bacterial chemical

Cat.No.S5515

Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
Penicillin G Procaine Bacterial chemical Chemical Structure

Chemical Structure

Molecular Weight: 588.72

Quality Control

Batch: S551501 DMSO]100 mg/mL]false]Water]5 mg/mL]false]]]false Purity: 99.91%
99.91

Chemical Information, Storage & Stability

Molecular Weight 588.72 Formula

C16H18N2O4S.C13H20N2O2.H2O

Storage (From the date of receipt) 3 years -20°C powder
CAS No. 6130-64-9 -- Storage of Stock Solutions

Synonyms Procaine benzylpenicillin,PGP Smiles O.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1.CC2(C)SC3C(NC(=O)CC4=CC=CC=C4)C(=O)N3C2C(O)=O

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (169.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 5 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05404373 Completed
Stroke Acute|Neuroprotection|Endovascular Treatment
Capital Medical University|Tianjin Huanhu Hospital
June 20 2022 Not Applicable
NCT05270525 Recruiting
COPD
Verona Pharma plc|University of Alabama at Birmingham
May 27 2022 Phase 2
NCT05232357 Unknown status
Gastrointestinal Neoplasms|Abnormality of Enteric Nervous System Morphology
Affiliated Hospital to Academy of Military Medical Sciences
March 1 2022 Early Phase 1

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