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Oxacillin sodium monohydrate Bacterial chemical

Cat.No.S2563

Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
Oxacillin sodium monohydrate Bacterial chemical Chemical Structure

Chemical Structure

Molecular Weight: 441.43

Quality Control

Chemical Information, Storage & Stability

Molecular Weight 441.43 Formula

C19H18N3O5S.Na.H2O

Storage (From the date of receipt)
CAS No. 7240-38-2 Download SDF Storage of Stock Solutions

Synonyms Methicillin Smiles CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+]

Solubility

In vitro
Batch:

Water : 88 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06282510 Recruiting
Candida Auris Infection|Colonization Asymptomatic
Mary K Hayden|Rush University Medical Center|RML Specialty Hospital
January 29 2024 Phase 4
NCT05971550 Not yet recruiting
Neisseria Gonorrhoeae Infection|Asymptomatic Pharyngeal Carriage
Assistance Publique - Hôpitaux de Paris
September 2023 Phase 3
NCT05100407 Completed
Multi-antibiotic Resistance
Kufa University
March 1 2022 --
NCT05197205 Unknown status
Sickle Cell Disease
Assistance Publique - Hôpitaux de Paris
February 1 2022 Not Applicable
NCT04597424 Active not recruiting
Unsafe Sex|Risk-Taking
ANRS Emerging Infectious Diseases
January 19 2021 Phase 3
NCT03869437 Completed
Bloodstream Infections
The University of Queensland|Shionogi
October 28 2019 Phase 2

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