Capreomycin Sulfate

Catalog No.S4234

For research use only.

Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.

Capreomycin Sulfate Chemical Structure

CAS No. 1405-37-4

Selleck's Capreomycin Sulfate has been cited by 1 Publication

Purity & Quality Control

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Biological Activity

Description Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.
In vitro

Capreomycin anchors Cu(2+) ion with an amino function of the α,β-diaminopropionic acid residue at pH around 5.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 750.78
Formula

C25H44N14O7.H2SO4

CAS No. 1405-37-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1CN=C(NC1C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)N2)CNC(=O)C(CCCN)N)CO)N)N.OS(=O)(=O)O

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04239326 Recruiting Diagnostic Test: targeted Next Generation Sequencing (tNGS) Tuberculosis Multidrug-Resistant Foundation for Innovative New Diagnostics Switzerland April 16 2021 --
NCT02496572 Unknown status Drug: Short course MDR-TB treatment regimen Multidrug Resistant Tuberculosis Medecins Sans Frontieres Netherlands|Ministry of Health Republic of Uzbekistan|Imperial College London September 2013 --
NCT02169141 Completed Other: Pharmacokinetics Tuberculosis University Medical Center Groningen|Republican Scientific and Practical Centre for Pulmonology and TB|National Institute for Public Health and the Environment (RIVM) November 2012 --

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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