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Ciprofloxacin (CPX) hydrochloride
Synonyms: Bay-09867
Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
Ciprofloxacin (CPX) hydrochloride Chemical Structure
CAS: 93107-08-5
Selleck's Ciprofloxacin (CPX) hydrochloride has been cited by 1 publication
Purity & Quality Control
Batch:
S500801
Water]
30 mg/mL]
false]
DMSO]
7 mg/mL]
false]
Ethanol]
Insoluble]
false
Purity:
98%
98
Ciprofloxacin (CPX) hydrochloride Related Products
| Related Targets | Topo I Topo II Topo IV | Click to Expand |
|---|---|---|
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Signaling Pathway
Choose Selective Topoisomerase Inhibitors
Biological Activity
| Description | Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases). | |
|---|---|---|
| Targets |
|
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT05828550 | Not yet recruiting | Patients withInfections Caused by S.Aureus Like Skin Infections Chest Infections Surgical Site Infections and Urinary Tract Infections |
Sohag University |
May 2023 | Not Applicable |
Chemical Information & Solubility
| Molecular Weight | 367.8 | Formula | C17H19ClFN3O3 |
| CAS No. | 93107-08-5 | SDF | -- |
| Smiles | Cl.OC(=O)C1=CN(C2CC2)C3=CC(=C(F)C=C3C1=O)N4CCNCC4 | ||
| Storage (From the date of receipt) | 3 years -20°C powder | ||
|
In vitro |
Water : 30 mg/mL DMSO : 7 mg/mL ( (19.03 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.) Ethanol : Insoluble |
Molecular Weight Calculator |
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In vivo Add solvents to the product individually and in order. |
In vivo Formulation Calculator |
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Preparing Stock Solutions
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In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
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Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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