Ciprofloxacin hydrochloride

Catalog No.S5008 Synonyms: CPX, Cetraxal, Ciloxan, Cipro, Bay-09867 hydrochloride

For research use only.

Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).

Ciprofloxacin hydrochloride Chemical Structure

CAS No. 93107-08-5

Purity & Quality Control

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Biological Activity

Description Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
Targets
DNA gyrase [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 367.8
Formula

C17H19ClFN3O3

CAS No. 93107-08-5
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05133258 Not yet recruiting Drug: ciprofloxacin and dexamethasone suspension Chronic Suppurative Otitis Media Dartmouth-Hitchcock Medical Center December 15 2021 Not Applicable
NCT04719637 Recruiting Device: PRDS-001 Renal Denervation Ultrasound System Chronic Heart Failure Otsuka Medical Devices Co. Ltd. Japan August 24 2021 Not Applicable
NCT04775238 Recruiting Other: Silver nanoparticles|Other: Copper nanoparticles Nosocomial Infections Sohag University February 27 2021 Not Applicable
NCT04525131 Recruiting Drug: CPX-POM Bladder Cancer CicloMed LLC November 25 2020 Phase 2
NCT04513548 Recruiting Drug: Ligelizumab|Drug: Placebo Chronic Spontaneous Urticaria|Cholinergic Urticaria|Cold Urticaria Novartis Pharmaceuticals|Novartis August 5 2020 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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