Catalog No.S3179 Synonyms: BRL-2064
Molecular Weight(MW): 422.36
Carbenicillin is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
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|Description||Carbenicillin is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.|
Carbenicillin (125 mg/L) completely suppresses the proliferation of Agrobacterium. Carbenicillin (250 mg/L-500 mg/L) enhances Callus fresh weight increase. Carbenicillin (125 mg/L) results in higher percentages of somatic embryos and larger numbers of somatic embryos from the individual callus.  Carbenicillin (1g/L) influences shoot formation negatively as the shooting frequency for leaf disc explants is reduced to 56% and for cotyledons to 51% after 2 months of culture of Nicotiana tabacum Petit Havana.  Carbenicillin prevents the development of mature somatic embryos, reduces early stage embryos by >90% and tissue growth by 50% of Sitka spruce.  The leukocytes of the patients does not release histamine on in vitro provocation with Carbenicillin (0.1 g/mL). 
|In vivo||Carbenicillin (0.1 g/mL) does not show any allergic drug reactions in cystic fibrosis patients, as evident by no significant levels of antibodies of IgE, IgG or IgM classes.  Carbenicillin (50 μg/mL) results in phytotoxicity in chrysanthemum and TOB, with an increase in the concentration, and with a parallel shift in the morphogenic capacity (SRC) of threshold survival levels (TSLs). Carbenicillin results in 100% acclimatization with no different morphological flowering characteristics following subculture in vitro three times in Chrysanthemum plantlets. |
-  TA Yu, et al. Bot. Bull. Acad. Sin, 2001, 42, 281-286.
-  Birgitte Nauerby, et al. Plant Science, 1997, 123 ,169- 177.
-  Sarma KS, et al. Journal of Experimental Botany, 1995, 46(11), 1779-1781.
|In vitro||Water||84 mg/mL (198.88 mM)|
|DMSO||5 mg/mL (11.83 mM)|
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