Carbenicillin disodium
Catalog No.S3179 Synonyms: BRL-2064
Molecular Weight(MW): 422.36
Carbenicillin is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
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Biological Activity
| Description | Carbenicillin is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity. |
|---|---|
| In vitro |
Carbenicillin (125 mg/L) completely suppresses the proliferation of Agrobacterium. Carbenicillin (250 mg/L-500 mg/L) enhances Callus fresh weight increase. Carbenicillin (125 mg/L) results in higher percentages of somatic embryos and larger numbers of somatic embryos from the individual callus. [1] Carbenicillin (1g/L) influences shoot formation negatively as the shooting frequency for leaf disc explants is reduced to 56% and for cotyledons to 51% after 2 months of culture of Nicotiana tabacum Petit Havana. [2] Carbenicillin prevents the development of mature somatic embryos, reduces early stage embryos by >90% and tissue growth by 50% of Sitka spruce. [3] The leukocytes of the patients does not release histamine on in vitro provocation with Carbenicillin (0.1 g/mL). [4] |
| In vivo | Carbenicillin (0.1 g/mL) does not show any allergic drug reactions in cystic fibrosis patients, as evident by no significant levels of antibodies of IgE, IgG or IgM classes. [4] Carbenicillin (50 μg/mL) results in phytotoxicity in chrysanthemum and TOB, with an increase in the concentration, and with a parallel shift in the morphogenic capacity (SRC) of threshold survival levels (TSLs). Carbenicillin results in 100% acclimatization with no different morphological flowering characteristics following subculture in vitro three times in Chrysanthemum plantlets. [5] |
Protocol
Solubility (25°C)
| In vitro | Water | 84 mg/mL (198.88 mM) |
|---|---|---|
| DMSO | 5 mg/mL (11.83 mM) | |
| Ethanol | Insoluble |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 422.36 |
|---|---|
| Formula | C17H16N2Na2O6S |
| CAS No. | 4800-94-6 |
| Storage | powder |
| in solvent | |
| Synonyms | BRL-2064 |
Bio Calculators
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