Netilmicin Sulfate

Catalog No.S4052

For research use only.

Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.

Netilmicin Sulfate Chemical Structure

CAS No. 56391-57-2

Selleck's Netilmicin Sulfate has been cited by 1 Publication

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.
In vitro

Netilmicin Sulfate is a semisynthetic derivative of sisomicin. It shows activity against aminoglycoside-resistant bacteria and much decreased chronic toxicity in animals relative to sisomicin, gentamicin and tobramycin. Netilmicin Sulfate shows high activity against E. coli, Klebsiella, Enterobacter, Citrobacter, Proteus spp and Staph. Aureus. In addition, 87% of indole-positive Proteus strains, 90.7% of Serratia and 83.5% of Ps. Aeruginosa strains are sensitive to Netilmicin Sulfate. [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 1441.55
Formula

C21H41N5O7.2.5H2SO4

CAS No. 56391-57-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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