Tedizolid (TR-700)

Catalog No.S5278

Tedizolid (TR-700) Chemical Structure

Molecular Weight(MW): 370.34

Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.

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Biological Activity

Description Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.

Protocol

References

Solubility (25°C)

In vitro DMSO 10 mg/mL (27.0 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 370.34
Formula

C17H15FN6O3

CAS No. 856866-72-3
Storage powder
in solvent
Synonyms N/A

Bio Calculators

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03746327 Not yet recruiting Drug: Sivextro 200 milligrams Oral Tablet Prostheses Infection Fundacion Clinic per a la Recerca Biomédica November 1 2019 Phase 4
NCT02620787 Completed Drug: Tedizolid|Procedure: Microdialysis Catheter Insertion Diabetes|Wound Infection|Healthy Volunteers Hartford Hospital|Merck Sharp & Dohme Corp. February 23 2016 Phase 1
NCT02477514 Completed Drug: midazolam|Drug: rosuvastatin|Drug: tedizolid phosphate Skin Diseases Bacterial Merck Sharp & Dohme Corp. June 2015 Phase 1
NCT02342418 Completed Drug: Tedizolid phosphate Obesity Amit.Pai|Merck Sharp & Dohme Corp.|Albany College of Pharmacy and Health Sciences March 2015 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID