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Tedizolid Bacterial chemical

Name: Tedizolid
Brand: Selleck Chemicals
SKU: S5278
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S5278

Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.

Tedizolid Bacterial chemical Chemical Structure

Quality Control

Batch: S527801 DMSO]10 mg/mL]false]]]false]]]false Purity: 99.69%

Cited in Nature Medicine for its top-tier quality
COA
NMR
SDS/MSDS
Datasheet

99.69

Related Targets	Integrase Antibiotics Anti-infection Fungal Antiviral COVID-19 Parasite Reverse Transcriptase HIV HCV Protease
Other Bacterial Inhibitors	BTZ043 Racemate Teicoplanin Pefloxacin Mesylate Ceftiofur Solithromycin 6-Methoxydihydrosanguinarine Proanthocyanidins Flagelin 22 Taurolidine Skatole

Solubility

In vitro
Batch:

DMSO : 10 mg/mL (27.0 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.500mg/ml (1.35mM)	Taking the 1 mL working solution as an example, add 50 μL of 10 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.125mg/ml (0.34mM)	Taking the 1 mL working solution as an example, add 50 μL of 2.5 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	370.34	Formula	C₁₇H₁₅FN₆O₃	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	856866-72-3	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	TR-700			SMILES	CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4CC(OC4=O)CO)F

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-07-07)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT05398679	RECRUITING	Endocarditis Infective	Fundacion Clinic per a la Recerca Biomédica	2022-08-17	PHASE4
NCT05534750	RECRUITING	Tuberculosis; Multidrug Resistant Tuberculosis	Assistance Publique - Hôpitaux de Paris	2023-04-20	PHASE2
NCT06609161	COMPLETED	Healthy	Merck Sharp & Dohme LLC	2024-07-16	PHASE1
NCT03746327	COMPLETED	Prostheses Infection	Fundacion Clinic per a la Recerca Biomédica	2020-02-13	PHASE4
NCT03176134	COMPLETED	Acute Bacterial Skin and Skin Structure Infections	Merck Sharp & Dohme LLC	2019-01-20	PHASE3
NCT03217565	COMPLETED	Gram-Positive Infections	Merck Sharp & Dohme LLC	2019-02-06	PHASE1

Tech Support

Handling Instructions

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