research use only

Benzathine penicilline Bacterial chemical

Cat.No.S5736

Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
Benzathine penicilline Bacterial chemical Chemical Structure

Chemical Structure

Molecular Weight: 909.12

Quality Control

Chemical Information, Storage & Stability

Molecular Weight 909.12 Formula

C48H56N6O8S2

Storage (From the date of receipt) 3 years -20°C powder
CAS No. 1538-09-6 -- Storage of Stock Solutions

Synonyms Benzathine penicillin G Smiles CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.C1=CC=C(C=C1)CNCCNCC2=CC=CC=C2

Solubility

In vitro
Batch:

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06391125 Not yet recruiting
Syphilis Infection|Benzathine Penicillin Adverse Reaction
Washington University School of Medicine
June 2024 Phase 3
NCT01944358 Completed
Serologic Response of Syphilis|Early Syphilis|High Risk Behavior
National Taiwan University Hospital|Far Eastern Memorial Hospital|Taichung Veterans General Hospital|National Cheng-Kung University Hospital|Chang Gung Memorial Hospital|Chi Mei Medical Hospital|Kaohsiung Medical University Chung-Ho Memorial Hospital|E-DA Hospital
January 2007 --

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