Tobramycin

Catalog No.S2514 Synonyms: NSC 180514

For research use only.

Tobramycin (NSC 180514) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.

Tobramycin Chemical Structure

CAS No. 32986-56-4

Selleck's Tobramycin has been cited by 1 Publication

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Tobramycin (NSC 180514) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 467.52369
Formula

C18H37N5O9

CAS No. 32986-56-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04964947 Recruiting Drug: Tobramycin Injection Wound Infection|Fractures Open|Surgical Site Infection Arun Aneja|United States Department of Defense|University of Kentucky January 10 2022 Phase 3
NCT05169229 Not yet recruiting Drug: Vancomycin + Tobramycin|Drug: Saline Arthroplasty Replacement Hip|Osteoarthritis Hip|Antibiotic Resistant Infection|Prosthetic Joint Infection University Hospital Linkoeping|Region Östergötland|The Swedish Research Council December 2021 Phase 2|Phase 3
NCT04297631 Completed Drug: Tobramycin Powder|Device: Vancomyscin Antibotics in Cementless Knees Washington University School of Medicine February 14 2020 Phase 4
NCT03904836 Completed Drug: Tobramycin Renal Dialysis|Renal Failure Chronic Maisonneuve-Rosemont Hospital January 31 2019 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Tobramycin | Tobramycin ic50 | Tobramycin price | Tobramycin cost | Tobramycin solubility dmso | Tobramycin purchase | Tobramycin manufacturer | Tobramycin research buy | Tobramycin order | Tobramycin mouse | Tobramycin chemical structure | Tobramycin mw | Tobramycin molecular weight | Tobramycin datasheet | Tobramycin supplier | Tobramycin in vitro | Tobramycin cell line | Tobramycin concentration | Tobramycin nmr