Home Microbiology Antineoplastic and Immunosuppressive Antibiotics inhibitor Tobramycin

research use only

Tobramycin Antineoplastic and Immunosuppressive Antibiotics inhibitor

Cat.No.S2514

Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.
Tobramycin Antineoplastic and Immunosuppressive Antibiotics inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 467.52369

Jump to

Quality Control

Batch: Purity: 99.87%
99.87

Solubility

In vitro
Batch:

Water : 94 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 467.52369 Formula

C18H37N5O9

 Storage (From the date of receipt)
CAS No. 32986-56-4 Download SDF Storage of Stock Solutions

Synonyms NSC 180514,Deoxykanamycin B, Nebramycin Factor 6 SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-07-14)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05361941 RECRUITING
Periprosthetic Joint Infections
Elute, Inc.
 2023-08-31
NCT05169229 RECRUITING
Arthroplasty, Replacement, Hip; Osteoarthritis, Hip; Antibiotic Resistant Infection; Prosthetic Joint Infection
University Hospital, Linkoeping
 2022-04-01 PHASE2
NCT04678154 RECRUITING
Post Operative Surgical Site Infection
Major Extremity Trauma Research Consortium
 2021-05-07 PHASE3
NCT04964947 ACTIVE_NOT_RECRUITING
Wound Infection; Fractures, Open; Surgical Site Infection
Massachusetts General Hospital
 2022-01-10 PHASE3
NCT06016088 COMPLETED
Cystic Fibrosis Lung; Respiratory Infections, Recurrent, Chronic; Pseudomonas Aeruginosa
Respirion Pharmaceuticals Pty Ltd
 2024-04-01 PHASE1; PHASE2
NCT06093191 COMPLETED
Bronchiectasis Adult; Pseudomonas Aeruginosa Infection
Jin-Fu Xu
 2023-10-18 PHASE4

Read more about Clinical Trials

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.