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Clindamycin Phosphate Antibiotics chemical

Cat.No.S2048

Clindamycin Phosphate (NSC 618653) is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.
Clindamycin Phosphate Antibiotics chemical Chemical Structure

Chemical Structure

Molecular Weight: 504.96

Quality Control

Batch: S204801 Water]101 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 98.82%
98.82

Chemical Information, Storage & Stability

Molecular Weight 504.96 Formula

C18H34ClN2O8PS

Storage (From the date of receipt)
CAS No. 24729-96-2 Download SDF Storage of Stock Solutions

Synonyms NSC 618653 Smiles CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)OP(=O)(O)O)O)O)C(C)Cl

Solubility

In vitro
Batch:

Water : 101 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

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% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05926869 Completed
Acne Vulgaris
Jinnah Postgraduate Medical Centre
August 1 2022 Phase 2
NCT05223400 Completed
Infection Bacterial
Alexandria University
March 1 2022 --
NCT04946500 Unknown status
Prosthetic Joint Infection|Staphylococcus
University Hospital Brest
May 15 2021 --

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