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Enrofloxacin

Name: Enrofloxacin
Brand: Selleck Chemicals
SKU: S3059
Rating: 5 (1 reviews)

Synonyms: BAY-Vp2674, PD160788

Catalog No.S3059 Purity: 99.99%

Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.

Enrofloxacin Chemical Structure

CAS: 93106-60-6

Purity & Quality Control

Batch: S305901 4-Methylpyridine] 30 mg/mL] false] DMSO] 1 mg/mL] false] Water] Insoluble] false Purity: 99.99%

99.99

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Biological Activity

Description	Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.

In vitro
In vitro	Enrofloxacin is a synthetic chemotherapeutic agent from the class of the fluoroquinolone carboxylic acid derivatives. It has antibacterial activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Enrofloxacin is believed to act by inhibiting bacterial DNA gyrase (a type-II topoisomerase), thereby preventing DNA supercoiling and DNA synthesis.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT03575312	Completed	Healthy	Fraunhofer-Institute of Toxicology and Experimental Medicine\|Federal Institute for Occupational Safety and Health (BAuA)/Germany)	April 27 2018	Not Applicable

References

Chemical Information & Solubility

Molecular Weight	359.39	Formula	C₁₉H₂₂FN₃O₃
CAS No.	93106-60-6	SDF	Download Enrofloxacin SDF
Smiles	CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

4-Methylpyridine : 30 mg/mL

DMSO : 1 mg/mL ( (2.78 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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