Tetracycline HCl

Catalog No.S2574 Synonyms: NCI-c55561

For research use only.

Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.

Tetracycline HCl Chemical Structure

CAS No. 64-75-5

Selleck's Tetracycline HCl has been cited by 4 Publications

Purity & Quality Control

Choose Selective Selection Antibiotics for Transfected Cell Inhibitors

Other Selection Antibiotics for Transfected Cell Products

Biological Activity

Description Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 480.9
Formula

C22H24N2O8.HCl

CAS No. 64-75-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04762134 Not yet recruiting Drug: Doxycycline Hyclate Bacterial Sexually Transmitted Diseases Jonathan Troy Grennan|Canadian Institutes of Health Research (CIHR)|British Columbia Centre for Disease Control April 1 2021 Phase 2|Phase 3
NCT02864550 Unknown status Drug: Doxycycline|Other: Placebo Syphilis|Sexually Transmitted Infections British Columbia Centre for Disease Control August 15 2019 Phase 4
NCT02188381 Recruiting Other: Stool Sample and Blood Sample Hypertension University of Florida|National Heart Lung and Blood Institute (NHLBI) July 2014 --

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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