Cefotaxime sodium

Catalog No.S4517

For research use only.

Cefotaxime sodium salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.

Cefotaxime sodium Chemical Structure

CAS No. 64485-93-4

Purity & Quality Control

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Biological Activity

Description Cefotaxime sodium salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.
In vitro

It has activity in presence of some beta-lactamases, both penicillinases and cephalosporinases of Gram negative and Gram positive bacteria. Its spectrum of activity includes most strains of bacterial pathogens responsible for septicaemia, respiratory tract infections, urinary tract infections, soft tissue infections, bone and joint infections, obstetric and gynaecological infections, and other various types of infections[1].

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 477.45
Formula

C16H17N5O7S2.Na

CAS No. 64485-93-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+]

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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