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Amikacin hydrate Selection Antibiotics for Transfected Cell inhibitor

Cat.No.S3122

Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.
Amikacin hydrate Selection Antibiotics for Transfected Cell inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 585.6+x18

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Chemical Information, Storage & Stability

Molecular Weight 585.6+x18 Formula

C22H43N5O13.xH2O

 Storage (From the date of receipt)
CAS No. 1257517-67-1 Download SDF Storage of Stock Solutions

Synonyms BAY416651 hydrate Smiles C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N.O

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Mass Concentration Volume Molecular Weight

In vivo
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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro

Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.
References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05555303 Recruiting
Tuberculosis Multidrug-Resistant
Rwanda Biomedical Centre|Institute of Tropical Medicine|World Health Organization
 March 1 2023 Phase 2
NCT05689450 Completed
Febrile Neutropenia (FN)
University Hospital Basel Switzerland
 December 21 2022 --
NCT05593601 Recruiting
Colonization Asymptomatic
Mahidol University
 November 24 2022 Phase 4
NCT05511129 Active not recruiting
COVID-19|Nosocomial Infection
Fondation Hôpital Saint-Joseph
 May 12 2022 --
NCT04239326 Completed
Tuberculosis Multidrug-Resistant
Foundation for Innovative New Diagnostics Switzerland
 April 16 2021 --

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