Amikacin hydrate

Synonyms: BAY416651 hydrate

Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.

Amikacin hydrate Chemical Structure

Amikacin hydrate Chemical Structure

CAS: 1257517-67-1

Selleck's Amikacin hydrate has been cited by 2 publications

Purity & Quality Control

Amikacin hydrate Related Products

Choose Selective Selection Antibiotics for Transfected Cell Inhibitors

Biological Activity

Description Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.
In vitro
In vitro

Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05555303 Recruiting
Tuberculosis Multidrug-Resistant
Rwanda Biomedical Centre|Institute of Tropical Medicine|World Health Organization
March 1 2023 Phase 2
NCT05689450 Recruiting
Febrile Neutropenia (FN)
University Hospital Basel Switzerland
December 21 2022 --
NCT05593601 Recruiting
Colonization Asymptomatic
Mahidol University
November 24 2022 Phase 4
NCT05511129 Active not recruiting
COVID-19|Nosocomial Infection
Fondation Hôpital Saint-Joseph
May 12 2022 --
NCT04239326 Completed
Tuberculosis Multidrug-Resistant
Foundation for Innovative New Diagnostics Switzerland
April 16 2021 --

Chemical Information & Solubility

Molecular Weight 585.6+x18 Formula

C22H43N5O13.xH2O

CAS No. 1257517-67-1 SDF Download Amikacin hydrate SDF
Smiles C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N.O
Storage (From the date of receipt)

In vivo
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In vivo Formulation Calculator

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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