Astrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis

163 views | Oct 18 2021

Jingjing Zhang et al. found unrecognized functions of astrocytic YAP in the prevention of demyelination through promoting cholesterol synthesis in EAE, and revealed a novel pathway of YAP/HMGCS1 for cholesterol synthesis in EAE pathology. [Read the Full Post]

Resveratrol ameliorates lipopolysaccharide-induced anxiety-like behavior by attenuating YAP-mediated neuro-inflammation and promoting hippocampal autophagy in mice

224 views | Oct 22 2020

Qiuyun Tian et al.suggested that inhibition of YAP pathway could be a potential therapeutic target for anxiety-like behavior induced by neuro-inflammation. [Read the Full Post]