Category

PI3K/Akt/mTOR
- PI3K
- mTOR
- Akt
- GSK-3
- ATM/ATR
- PDK
- AMPK
- DNA-PK
- PTEN
- MELK
- PP2A
- PIKfyve
- PI4K
Epigenetics
- HDAC
- AMPK
- PARP
- JAK
- Pim
- HIF
- PKC
- Aurora Kinase
- Sirtuin
- DNA Methyltransferase
- Histone Demethylase
- Epigenetic Reader Domain
- Histone Acetyltransferase
- Histone Methyltransferase
- JMJD
- PRMT
- COMT
- EZH1/2
- NSD3
- LSD1
- FTO
- PAD
- MicroRNA
- SAM MTase
- PPMTase
- WDR5
- SMYD
- DOT1
- HNMT
- SETD
- G9a/GLP
- MLL
Methylation
- DNA Methyltransferase
- COMT
- NSD3
- FTO
- SAM MTase
- PPMTase
- WDR5
- SMYD
- DOT1
- HNMT
- SETD
- G9a/GLP
- MLL
- JMJD
- PRMT
- EZH1/2
- LSD1
Immunology & Inflammation
- CD markers
- PD-1/PD-L1
- COX
- CCR
- Histamine Receptor
- IL Receptor
- Anti-infection
- CXCR
- NOD
- AhR
- LTR
- IDO/TDO
- ROS
- MALT
- NADPH-oxidase
- Nrf2
- gp120/CD4
- TLR
- NOS
- Immunology & Inflammation related
- PKR
- PGES
- AKR1C
- IFN
- Heme Oxygenase
- MyD88
- FLAP
- STING
- Parasite
- cGAS
- Galectin
- Prostaglandin Receptor
- MmpL3
- Arginase
- MIF
- Nur77
- Glutathione
- β-lactamase
- Pyroptosis
- TBK1
- FKBP
- IRAK
- TpoR
- Interleukins
- Neuraminidase
- Complement System
- NLRP3
- eIF
- SPHK
- SIK
- TRIF
- PGDS
Protein Tyrosine Kinase
- VEGFR
- EGFR
- PDGFR
- c-Met
- HER2
- IGF-1R
- FLT3
- FGFR
- Bcr-Abl
- c-Kit
- Src
- ALK
- Syk
- Tie-2
- FAK
- c-RET
- BTK
- ACK
- Ephrin receptor
- CSF-1R
- DYRK
- Trk receptor
- RON
- Fer kinase
- Pyk2
- ROS1
- Mertk
- Axl
- Tyro3
- DDR
Angiogenesis
- VEGFR
- JAK
- EGFR
- PDGFR
- HER2
- FLT3
- FGFR
- HIF
- VDA
- Bcr-Abl
- Src
- ALK
- Syk
- FAK
- BTK
Apoptosis
- PD-1/PD-L1
- Bcl-2
- Caspase
- p53
- TNF-alpha
- Mdm2
- Survivin
- Ras
- c-RET
- RIP kinase
- PERK
- ASK
- IAP
- Ferroptosis
- Myc
- Nur77
- PFKFB
- Apoptosis related
- OXPHOS
- Heme Oxygenase
- cytohesin
- Bcl-6
- Thymidylate Synthase
- Pyroptosis
- PKD
- FKBP
- DAPK
Autophagy
- Autophagy
- Nrf2
- CXCR
- LRRK2
- cGAS
- FKBP
- LC3
- ULK
- Mitophagy
- Heme Oxygenase
- OGA
ER stress & UPR
- JNK
- HSP (HSP90)
- PERK
- ASK
- IRE1
- eIF
- PKR
- PDI
JAK/STAT
- JAK
- STAT
- EGFR
- Pim
MAPK
- S6 Kinase
- MEK
- Raf
- p38 MAPK
- JNK
- Ras
- TOPK
- ERK
- ASK
- KLF
- TAK1
- Mixed Lineage Kinase
- MNK
- MAP4K
Cytoskeletal Signaling
- Akt
- Bcr-Abl
- Wnt/beta-catenin
- PKC
- FAK
- HSP (HSP90)
- Kinesin
- ROCK
- Microtubule Associated
- Integrin
- MPS1
- PAK
- Dynamin
- Actin
- Gap-Junction
- PORCN
- TACC3
- MLCK
Cell Cycle
- CDK
- DNA/RNA Synthesis
- PD-1/PD-L1
- Ras
- Aurora Kinase
- HSP (HSP90)
- Kinesin
- Chk
- ROCK
- Microtubule Associated
- DHFR
- PLK
- APC
- Wee1
- PERK
- Rho
- PAK
- MPS1
- Casein Kinase
- DYRK
- Myc
- TOPK
- Serine/threonin kinase
- FOXM1
- Nur77
- TACC3
- PP2A
- RUNX
- Haspin Kinase
- PFKFB
- LIM kinase
- BMI-1
- eIF
- Choline kinase
- DOCK1
TGF-beta/Smad
- TGF-beta/Smad
- Bcr-Abl
- PKC
- ROCK
DNA Damage/DNA Repair
- HDAC
- ATM/ATR
- PARP
- DNA/RNA Synthesis
- PPAR
- Sirtuin
- Topoisomerase
- DNA-PK
- DHFR
- Telomerase
- High-mobility Group
- DNA alkylator
- MTH1
- Casein Kinase
- RNR
- SMN
- Nucleoside Analog/Antimetabolite
- LIM kinase
- RAD51
- CRISPR/Cas9
- BMI-1
- Thymidylate Synthase
- eIF
- G-quadruplex
Stem Cells & Wnt
- GSK-3
- JAK
- STAT
- TGF-beta/Smad
- Wnt/beta-catenin
- ROCK
- Gamma-secretase
- Hedgehog/Smoothened
- PKA
- ERK
- OCT
- KLF
- Stemness kinase
- Casein Kinase
- SFRP
- Fascin
- PORCN
- Notch
Hippo
- YAP
- MAP4K
- MST
Ubiquitin
- Proteasome
- DUB
- p97
- SUMO
- E2 conjugating
- E1 Activating
- E3 Ligase
Neuronal Signaling
- Calcium Channel
- Beta Amyloid
- 5-HT Receptor
- COX
- Gamma-secretase
- GluR
- Adrenergic Receptor
- AChR
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GABA Receptor
- P-gp
- P2 Receptor
- Cannabinoid Receptor
- OX Receptor
- CGRP Receptor
- MT Receptor
- MAO
- FAAH
- Trk receptor
- CaMK
- NMDAR
- BACE
- GlyT
- Neurokinin Receptor
- Serotonin Transporter
- Notch
- Neurotensin Receptor
- CCK receptor
- Melanocortin Receptor
- NPY receptor
- Imidazoline Receptor
- COMT
- Adenosine Deaminase
- Adenosine Kinase
- BChE
- EAAT
- TRP Channel
- Sigma Receptor
NF-κB
- HDAC
- NF-κB
- IκB/IKK
- ROS
- MALT
- Nrf2
- NOD
GPCR & G Protein
- Ras
- 5-HT Receptor
- CCR
- GluR
- Adrenergic Receptor
- AChR
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GPR
- P2 Receptor
- Cannabinoid Receptor
- Endothelin Receptor
- S1P Receptor
- Hedgehog/Smoothened
- SGLT
- LPA Receptor
- OX Receptor
- CGRP Receptor
- MT Receptor
- PAFR
- PKA
- Glucagon Receptor
- CaSR
- CXCR
- Adenosine Receptor
- cAMP
- Vasopressin Receptor
- TAAR
- LTR
- DOCK1
- GNRH Receptor
- FPR
- CRFR
- Bradykinin Receptor
- Neurokinin Receptor
- Bombesin Receptor
- AdipoR
- PKG
- Sigma Receptor
- Angiotensin Receptor
- Neurotensin Receptor
- RGS
- Melanocortin Receptor
- PAR
- NPY receptor
- GRK
- Imidazoline Receptor
- GPCR19
- Guanylate Cyclase
- TSH Receptor
- CCK receptor
- PKD
- Leukotriene
- Prostaglandin Receptor
- Taste Receptor
- GHSR
Endocrinology & Hormones
- Adrenergic Receptor
- 5-alpha Reductase
- Estrogen/progestogen Receptor
- Androgen Receptor
- RAAS
- Opioid Receptor
- Aromatase
- GPR
- Glucocorticoid Receptor
- PGES
- TSH Receptor
- GNRH Receptor
- GHSR
- Mineralocorticoid Receptor
- ACE
- THR
- CCK receptor
- PGDS
Transmembrane Transporters
- CD markers
- Calcium Channel
- Sodium Channel
- ATPase
- Chloride Channel
- Potassium Channel
- GluR
- AChR
- GABA Receptor
- P-gp
- Proton Pump
- CFTR
- P2 Receptor
- SGLT
- OCT
- NMDAR
- GlyT
- GLUT
- CRM1
- NKCC
- VDAC
- NBC
- MTP
- NCX
- VMAT
- GlyR
- BCRP
- MCT
- Amino acid transporter
- TRP Channel
- OAT
- OATP
- Aquaporin
- Mechanosensitive Channel
- EAAT
Metabolism
- PPAR
- P450 (e.g. CYP17)
- HSP (HSP90)
- PDE
- Hydroxylase
- Factor Xa
- DHFR
- Aminopeptidase
- Dehydrogenase
- Procollagen C Proteinase
- Phospholipase (e.g. PLA)
- Carbonic Anhydrase
- Phosphorylase
- Liver X Receptor
- FAAH
- Acyltransferase
- Vitamin
- Thioredoxin
- phosphatase
- Lipoxygenase
- Lipase
- NAMPT
- FXR
- Retinoid Receptor
- Serine/threonin kinase
- IDO/TDO
- Transferase
- PKM
- FOX
- Casein Kinase
- HMG-CoA Reductase
- Fatty Acid Synthase
- GLUT
- LDL
- CETP
- Decarboxylase
- Adenosine Deaminase
- PGC-1α
- RUNX
- Adenosine Kinase
- SCD
- Mitochondrial Metabolism
- PDHK
- LDH
- Neprilysin
- Glucosylceramide Synthase
- PAI-1
- FTO
- γGCS
- FAO
- SREBP
- Leukotriene
- PARG
- GTPCH
- CPT
- PCSK9
- Epoxide Hydrolase
- FTase
- Acetyl-CoA carboxylase
- PGDS
- SGK
- ATP-citrate lyase
- ACE
- Thioredoxin Reductase
- Carbohydrate Metabolism
- Mannosidase
- THR
- Xanthine Oxidase
- CPSase
- Aldose Reductase
- Glutathione
- OXPHOS
- PREP
- AdipoR
- FABP
- Peroxidases
- ROR
- PP2A
Proteases
- Proteasome
- Caspase
- Aminopeptidase
- Gamma-secretase
- HCV Protease
- DPP-4
- HIV Protease
- MMP
- Thrombin
- Acyltransferase
- Glutaminase
- Tyrosinase
- Serine Protease
- Cysteine Protease
- MALT
- SGK
- PREP
- 3C-Like Protease
- PCSK9
- DPP-2
- PGDS
- Cathepsin B
- Neprilysin
Microbiology
- HCV Protease
- Integrase
- Reverse Transcriptase
- HIV Protease
- Anti-infection
- Fungal
- CMV
- Neuraminidase
- Parasite
- Thioredoxin Reductase
- β-lactamase
- 3C-Like Protease
- COVID-19
- Ribosomal Peptidyl Transferase
Others
- ADC Cytotoxin
- ADC Linker
- Drug-Linker Conjugates for ADC
- Antineoplastic and Immunosuppressive Antibiotics
- Selection Antibiotics for Transfected Cell
- Antibiotics for Mammalian Cell Culture
- Antibiotics for Plant Cell Culture
- Hydrotropic Agents
- Dyes
- PROTAC
- PROTAC Linker
- E3 ligase Ligand
- Target Protein Ligand
- Others

Myc

Nucleotide variation in histone H2BL drives crossalk of histone modification and promotes tumour cell proliferation by upregulating c-Myc

3 views | Mar 30 2021

Lei Zhang et al. revealed that an H2BK5ac-H2BK120ubi crosstalk which regulates gene transcription. [Read the Full Post]

Antiviral activity of PLK1-targeting siRNA delivered by lipid nanoparticles in HBV-infected hepatocytes

88 views | Aug 10 2020

Adrien Foca et al. emphasized that a specific PLK1 inhibition could help in achieving an improved HBsAg loss in CHB patients, likely in combination with other HBsAg-targeting strategies. [Read the Full Post]

Choose Your Country or Region

By Signaling Pathways

By product type

Category

Archives

Popular Post

Myc

Nucleotide variation in histone H2BL drives crossalk of histone modification and promotes tumour cell proliferation by upregulating c-Myc

Antiviral activity of PLK1-targeting siRNA delivered by lipid nanoparticles in HBV-infected hepatocytes