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ER stress & UPR
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MAPK
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TGF-beta/Smad
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DNA Damage/DNA Repair
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- DNA/RNA Synthesis
- Sirtuin
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- Nucleoside Analog/Antimetabolite
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- eIF
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- CRISPR/Cas9
- BMI-1
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Stem Cells & Wnt
- GSK-3
- JAK
- STAT
- TGF-beta/Smad
- Wnt/beta-catenin
- ROCK
- Gamma-secretase
- Hedgehog/Smoothened
- OCT
- KLF
- Stemness kinase
- Casein Kinase
- Fascin
- PORCN
- Notch
Hippo
- YAP
- MAP4K
- MST
Ubiquitin
- Proteasome
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Neuronal Signaling
- Beta Amyloid
- 5-HT Receptor
- COX
- Gamma-secretase
- GluR
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- AChR
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- GlyT
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- Notch
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NF-κB
- HDAC
- NF-κB
- IκB/IKK
- NOD
GPCR & G Protein
- 5-HT Receptor
- CCR
- Adrenergic Receptor
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GPR
- Cannabinoid Receptor
- Endothelin Receptor
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- Hedgehog/Smoothened
- SGLT
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- PAFR
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- GHSR
- CCK receptor
- DOCK1
- Leukotriene
- FPR
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- Neurokinin Receptor
- PKG
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Endocrinology & Hormones
- Adrenergic Receptor
- 5-alpha Reductase
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- Androgen Receptor
- RAAS
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- ACE
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Transmembrane Transporters
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- MCT
- Amino acid transporter
- OAT
- OATP
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- VDAC
Metabolism
- PPAR
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- HSP (HSP90)
- PDE
- Hydroxylase
- Factor Xa
- DHFR
- Dehydrogenase
- Procollagen C Proteinase
- Phospholipase (e.g. PLA)
- Carbonic Anhydrase
- Phosphorylase
- MAO
- Liver X Receptor
- FAAH
- Acyltransferase
- AhR
- IDO/TDO
- Ferroptosis
- PKM
- FOX
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- LDL
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- Transferase
- Decarboxylase
- phosphatase
- Vitamin
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- FXR
- HMG-CoA Reductase
- Lipoxygenase
- Lipase
- NAMPT
- CETP
- Serine/threonin kinase
- Casein Kinase
- Retinoid Receptor
- Carbohydrate Metabolism
- Glutathione
- THR
- PREP
- AdipoR
- Xanthine Oxidase
- Peroxidases
- Aldose Reductase
- PP2A
- OXPHOS
- RUNX
- FABP
- cGAS
- ROR
- SCD
- PGC-1α
- LDH
- SREBP
- PAI-1
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- FAO
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- GTPCH
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- SGK
- Leukotriene
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- PCSK9
- Mannosidase
- Acetyl-CoA carboxylase
- CPSase
- ATP-citrate lyase
- ACE
Proteases
- Proteasome
- Caspase
- Gamma-secretase
- HCV Protease
- DPP-4
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- MMP
- Thrombin
- Acyltransferase
- Glutaminase
- Tyrosinase
- Serine Protease
- Cysteine Protease
- SGK
- PREP
- 3C-Like Protease
- PCSK9
Microbiology
- HCV Protease
- Integrase
- Reverse Transcriptase
- HIV Protease
- Anti-infection
- Parasite
- Thioredoxin Reductase
- β-lactamase
- 3C-Like Protease
- COVID-19
- Ribosomal Peptidyl Transferase
Others
- ADC Cytotoxin
- ADC Linker
- Drug-Linker Conjugates for ADC
- Antineoplastic and Immunosuppressive Antibiotics
- Selection Antibiotics for Transfected Cell
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- Antibiotics for Plant Cell Culture
- Hydrotropic Agents
- Dyes
- PROTAC
- PROTAC Linker
- E3 ligase Ligand
- Target Protein Ligand
- Others

c-Myc

Antiviral activity of PLK1-targeting siRNA delivered by lipid nanoparticles in HBV-infected hepatocytes

75 views | Aug 10 2020

Adrien Foca et al. emphasized that a specific PLK1 inhibition could help in achieving an improved HBsAg loss in CHB patients, likely in combination with other HBsAg-targeting strategies. [Read the Full Post]

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c-Myc

Antiviral activity of PLK1-targeting siRNA delivered by lipid nanoparticles in HBV-infected hepatocytes