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TEAD

Combination of Ocimum sanctum extract and Levetiracetam ameliorates cognitive dysfunction and hippocampal architecture in rat model of Alzheimer's disease

33 views | Jan 03 2022

H S Nandini et al. provided evidence for use of OSE, LEV and OSE+LEV against AD and epilepsy associated with AD in Aβ induced AD animal model. [Read the Full Post]

In silico evaluation of the downstream effect of mutated glucagon is consistent with higher blood glucose homeostasis in Galliformes and Strigiformes

122 views | Oct 11 2021

Karim Mahnam et al. suggested this mutation, which leaded to stronger binding affinity of mutated glucagon to its receptor, might be a driving force for higher blood glucose homeostasis in the related birds. [Read the Full Post]

Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid

126 views | Oct 10 2021

Léa Mélin et al. found that LM98 reduced the expression of CTGF and Cyr61, inhibited MDA-MB-231 breast cancer cell migration and arrested cell cycling in the S phase during cell division. [Read the Full Post]

Treatment outcomes of erlotinib plus gemcitabine as late-line chemotherapy in unresectable pancreatic cancer

324 views | Jun 16 2021

Takafumi Mie et al. found that benefits of erlotinib plus gemcitabine as late-line chemotherapy were limited, particularly with respect to PFS. [Read the Full Post]