Choose Your Country or Region

Category

PI3K/Akt/mTOR
- PI3K
- mTOR
- Akt
- GSK-3
- ATM/ATR
- PDK
- AMPK
- DNA-PK
- PTEN
- MELK
- PP2A
- PIKfyve
- PI4K
Epigenetics
- HDAC
- AMPK
- PARP
- JAK
- Pim
- HIF
- PKC
- Aurora Kinase
- Sirtuin
- DNA Methyltransferase
- Histone Demethylase
- Epigenetic Reader Domain
- Histone Acetyltransferase
- Histone Methyltransferase
- MLL
- JMJD
- COMT
- PRMT
- NSD3
- EZH1/2
- FTO
- LSD1
- MicroRNA
- PAD
- SAM MTase
- PPMTase
- WDR5
- SMYD
- DOT1
- HNMT
- SETD
- G9a/GLP
Methylation
- DNA Methyltransferase
- COMT
- NSD3
- FTO
- SAM MTase
- PPMTase
- WDR5
- SMYD
- DOT1
- HNMT
- SETD
- G9a/GLP
- MLL
- JMJD
- PRMT
- EZH1/2
- LSD1
Immunology & Inflammation
- CD markers
- PD-1/PD-L1
- COX
- CCR
- Histamine Receptor
- IL Receptor
- CXCR
- Anti-infection
- NOD
- AhR
- LTR
- IDO/TDO
- ROS
- MALT
- NADPH-oxidase
- Nrf2
- gp120/CD4
- TLR
- NOS
- Immunology & Inflammation related
- PKR
- PGES
- IFN
- AKR1C
- MyD88
- FLAP
- Heme Oxygenase
- Parasite
- cGAS
- STING
- Galectin
- MmpL3
- Arginase
- Prostaglandin Receptor
- MIF
- Nur77
- Glutathione
- β-lactamase
- Pyroptosis
- FKBP
- TBK1
- TpoR
- IRAK
- Neuraminidase
- Complement System
- Interleukins
- eIF
- SPHK
- NLRP3
- TRIF
- PGDS
- SIK
Protein Tyrosine Kinase
- VEGFR
- MEK
- EGFR
- PDGFR
- c-Met
- HER2
- IGF-1R
- FLT3
- FGFR
- Bcr-Abl
- c-Kit
- Src
- ALK
- Syk
- Tie-2
- FAK
- c-RET
- BTK
- ACK
- Ephrin receptor
- DYRK
- CSF-1R
- Trk receptor
- RON
- Fer kinase
- Pyk2
- ROS1
- Mertk
- Axl
- Tyro3
- DDR
Angiogenesis
- VEGFR
- JAK
- EGFR
- PDGFR
- HER2
- FLT3
- FGFR
- HIF
- VDA
- Bcr-Abl
- Src
- ALK
- Syk
- FAK
- BTK
Apoptosis
- PD-1/PD-L1
- Bcl-2
- Caspase
- p53
- TNF-alpha
- Mdm2
- Survivin
- Ras
- c-RET
- RIP kinase
- PERK
- ASK
- IAP
- Ferroptosis
- Myc
- Nur77
- PFKFB
- Apoptosis related
- OXPHOS
- TRADD
- Heme Oxygenase
- cytohesin
- Bcl-6
- Thymidylate Synthase
- Pyroptosis
- PKD
- FKBP
- DAPK
Autophagy
- Autophagy
- Nrf2
- CXCR
- LRRK2
- cGAS
- FKBP
- LC3
- ULK
- Mitophagy
- Heme Oxygenase
- OGA
ER stress & UPR
- JNK
- HSP (HSP90)
- PERK
- ASK
- IRE1
- ATF-6
- eIF
- PKR
- PDI
JAK/STAT
- JAK
- STAT
- EGFR
- Pim
MAPK
- S6 Kinase
- MEK
- Raf
- p38 MAPK
- JNK
- Ras
- TOPK
- ERK
- ASK
- KLF
- TAK1
- Mixed Lineage Kinase
- MNK
- MAPKAPK2
- MAP4K
Cytoskeletal Signaling
- Akt
- Bcr-Abl
- Wnt/beta-catenin
- PKC
- FAK
- HSP (HSP90)
- Kinesin
- ROCK
- Microtubule Associated
- Integrin
- MPS1
- Dynamin
- PAK
- Actin
- Gap-Junction
- PORCN
- TACC3
- MLCK
- Cardiac Myosin
Cell Cycle
- CDK
- DNA/RNA Synthesis
- PD-1/PD-L1
- Ras
- Aurora Kinase
- HSP (HSP90)
- Kinesin
- Chk
- ROCK
- Microtubule Associated
- DHFR
- PLK
- APC
- Wee1
- Serine/threonin kinase
- Rho
- PERK
- PAK
- MPS1
- Casein Kinase
- DYRK
- Myc
- TOPK
- FOXM1
- Nur77
- TACC3
- PP2A
- RUNX
- Haspin Kinase
- PFKFB
- LIM kinase
- BMI-1
- DOCK
- eIF
- Mad2
- Choline kinase
TGF-beta/Smad
- TGF-beta/Smad
- Bcr-Abl
- PKC
- ROCK
DNA Damage/DNA Repair
- HDAC
- ATM/ATR
- PARP
- DNA/RNA Synthesis
- PPAR
- Sirtuin
- Topoisomerase
- DNA-PK
- DHFR
- Telomerase
- High-mobility Group
- DNA alkylator
- MTH1
- Casein Kinase
- RNR
- SMN
- Nucleoside Analog/Antimetabolite
- LIM kinase
- RAD51
- FENs
- CRISPR/Cas9
- Pax
- BMI-1
- OGG1
- Thymidylate Synthase
- eIF
- G-quadruplex
Stem Cells & Wnt
- GSK-3
- JAK
- STAT
- TGF-beta/Smad
- Wnt/beta-catenin
- ROCK
- Gamma-secretase
- Hedgehog/Smoothened
- PKA
- ERK
- OCT
- KLF
- Stemness kinase
- Casein Kinase
- SFRP
- Fascin
- PORCN
- Notch
Hippo
- YAP
- TEAD
- MAP4K
- MST
Ubiquitin
- Proteasome
- DUB
- p97
- SUMO
- E2 conjugating
- E1 Activating
- E3 Ligase
Neuronal Signaling
- Calcium Channel
- Beta Amyloid
- 5-HT Receptor
- COX
- Gamma-secretase
- GluR
- Adrenergic Receptor
- AChR
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GABA Receptor
- P-gp
- P2 Receptor
- Cannabinoid Receptor
- OX Receptor
- CGRP Receptor
- MT Receptor
- MAO
- FAAH
- Trk receptor
- CaMK
- NMDAR
- BACE
- GlyT
- Serotonin Transporter
- Neurokinin Receptor
- Neurotensin Receptor
- Notch
- Melanocortin Receptor
- CCK receptor
- NPY receptor
- Imidazoline Receptor
- COMT
- Adenosine Deaminase
- Adenosine Kinase
- BChE
- TRP Channel
- EAAT
- Sigma Receptor
NF-κB
- HDAC
- NF-κB
- IκB/IKK
- ROS
- MALT
- Nrf2
- NOD
GPCR & G Protein
- Ras
- 5-HT Receptor
- CCR
- GluR
- Adrenergic Receptor
- AChR
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GPR
- P2 Receptor
- Cannabinoid Receptor
- Endothelin Receptor
- S1P Receptor
- Hedgehog/Smoothened
- SGLT
- LPA Receptor
- OX Receptor
- CGRP Receptor
- MT Receptor
- PAFR
- PKA
- CaSR
- LTR
- Glucagon Receptor
- CXCR
- Adenosine Receptor
- cAMP
- Vasopressin Receptor
- TAAR
- GHSR
- FPR
- GNRH Receptor
- CRFR
- Neurokinin Receptor
- Bradykinin Receptor
- Bombesin Receptor
- PKG
- AdipoR
- Angiotensin Receptor
- Sigma Receptor
- RGS
- Neurotensin Receptor
- Parathyroid Hormone Receptor
- PAR
- Melanocortin Receptor
- DOCK
- GRK
- NPY receptor
- GPCR19
- Imidazoline Receptor
- Guanylate Cyclase
- TSH Receptor
- CCK receptor
- PKD
- Leukotriene
- Prostaglandin Receptor
- Taste Receptor
Endocrinology & Hormones
- Adrenergic Receptor
- 5-alpha Reductase
- Estrogen/progestogen Receptor
- Androgen Receptor
- RAAS
- Opioid Receptor
- Aromatase
- GPR
- Glucocorticoid Receptor
- PGES
- TSH Receptor
- GNRH Receptor
- GHSR
- Mineralocorticoid Receptor
- ACE
- THR
- CCK receptor
- PGDS
Transmembrane Transporters
- CD markers
- Calcium Channel
- Sodium Channel
- ATPase
- Chloride Channel
- Potassium Channel
- GluR
- AChR
- GABA Receptor
- P-gp
- Proton Pump
- CFTR
- P2 Receptor
- SGLT
- OCT
- NMDAR
- GlyT
- GLUT
- CRM1
- NKCC
- VDAC
- NCX
- MTP
- VMAT
- GlyR
- BCRP
- MCT
- Amino acid transporter
- TRP Channel
- OAT
- OATP
- VRAC
- Aquaporin
- Mechanosensitive Channel
- EAAT
Metabolism
- PPAR
- P450 (e.g. CYP17)
- HSP (HSP90)
- PDE
- Hydroxylase
- Factor Xa
- DHFR
- Aminopeptidase
- Dehydrogenase
- Procollagen C Proteinase
- Phospholipase (e.g. PLA)
- Carbonic Anhydrase
- Phosphorylase
- Liver X Receptor
- FAAH
- Acyltransferase
- Vitamin
- phosphatase
- Thioredoxin
- Lipoxygenase
- Lipase
- FXR
- NAMPT
- Retinoid Receptor
- Serine/threonin kinase
- IDO/TDO
- Transferase
- PKM
- Casein Kinase
- HMG-CoA Reductase
- FOX
- GLUT
- Fatty Acid Synthase
- CETP
- LDL
- Decarboxylase
- PGC-1α
- Serine hydrolase
- RUNX
- Adenosine Deaminase
- 3-MST
- SCD
- Adenosine Kinase
- PDHK
- Catalase
- LDH
- Mitochondrial Metabolism
- Glucosylceramide Synthase
- PAI-1
- Neprilysin
- γGCS
- FAO
- FTO
- Leukotriene
- PARG
- GTPCH
- SREBP
- PCSK9
- Epoxide Hydrolase
- CPT
- Acetyl-CoA carboxylase
- PGDS
- FTase
- ATP-citrate lyase
- ACE
- SGK
- Carbohydrate Metabolism
- Thioredoxin Reductase
- THR
- Mannosidase
- Xanthine Oxidase
- CPSase
- Aldose Reductase
- Glutathione
- OXPHOS
- Mitochondrial pyruvate carrier
- PREP
- AdipoR
- FABP
- glucocerebrosidase
- Peroxidases
- ROR
- CAR
- PP2A
Proteases
- HDAC
- Proteasome
- Caspase
- Aminopeptidase
- Gamma-secretase
- HCV Protease
- DPP-4
- HIV Protease
- MMP
- Thrombin
- Acyltransferase
- Glutaminase
- Tyrosinase
- Serine Protease
- Cysteine Protease
- MALT
- SGK
- PREP
- 3C-Like Protease
- PCSK9
- DPP-2
- PGDS
- Cathepsin B
- Neprilysin
Microbiology
- HCV Protease
- Integrase
- Reverse Transcriptase
- HIV Protease
- Anti-infection
- HCV
- HBV
- HIV
- Fungal
- CMV
- Neuraminidase
- Parasite
- Antibiotics
- Thioredoxin Reductase
- Antiviral
- β-lactamase
- Bacterial
- 3C-Like Protease
- Enterovirus
- COVID-19
- Ribosomal Peptidyl Transferase
- Influenza Virus
- SARS-CoV
- RSV
- HPV
- HSV
Others
- ADC Cytotoxin
- ADC Linker
- Drug-Linker Conjugates for ADC
- Antineoplastic and Immunosuppressive Antibiotics
- Selection Antibiotics for Transfected Cell
- Antibiotics for Mammalian Cell Culture
- Antibiotics for Plant Cell Culture
- Hydrotropic Agents
- Dyes
- PROTAC
- PROTAC Linker
- E3 ligase Ligand
- Target Protein Ligand
- Others
- Antibody-Drug Conjugate

Archives

Popular Post

ESKM, a novel therapeutic agent for sensitive and resistant PH+ leukemias

Effects of PARP inhibitors in BRCA gene-mutated ovarian cancer

The mechanism of resistance to JAK2 inhibitor in myeloproliferative neoplasms patients

DASATINIB; An inhibitor of Receptor Tyrosine Kinase

GP130/JAK/STAT3 signaling pathway induces multiple myeloma

P2 Receptor

A Platelet/CMC coupled with offline UPLC-QTOF-MS/MS for screening antiplatelet activity components from aqueous extract of Danshen

889 views | Apr 30 2018

Chen Y et al. suggested their retention time was closely related to the antiplatelet aggregation activities. This study provides a rapid, effective and novel method for screening the potential antiplatelet activity components from Chinese herb medicines. [Read the Full Post]

MRS2578 is a selective antagonist of P2Y6 nucleotide receptors

2851 views | Jul 29 2013

MRS 2578 (10 μM) significant reduces TNF-α–induced proinflammatory gene expression in HMEC-1 cells. [Read the Full Post]