A Dentin Biomimetic Remineralization Material with an Ability to Stabilize Collagen

10 views | Oct 23 2022

Siying Tao et al. indicated that PNG had great potential to combat early dentin caries for future clinical application. [Read the Full Post]

Target and drug predictions for SARS-CoV-2 infection in hepatocellular carcinoma patients

3 views | Oct 23 2022

Luhong Wang et al. thought that COVID-19 and HCC were closely linked at the molecular level and proposes drugs that might play an important role in HCC patients with COVID-19. [Read the Full Post]

The Natural Ligand for Metalloproteinase-A Multifaceted Drug Target

104 views | Mar 15 2022

Saranya Shivashankar et al. strengthened the significance of these phytochemicals as promising lead candidates for the treatment of snakebite envenomation. [Read the Full Post]

SNAI1-mediated transcriptional regulation of epithelial-to-mesenchymal transition genes in breast cancer stem cells

169 views | Nov 29 2021

Digvijay Singh et al. identified MMPs, a downstream effector in the SNAI1-mediated EMT regulation. [Read the Full Post]

Specific Inhibitor of Matrix Metalloproteinase Decreases Tumor Invasiveness After Radiofrequency Ablation in Liver Tumor Animal Model

241 views | Mar 29 2021

An-Na Jiang et al. suggested that targeting the MMP process with the specific inhibition could help to increase overall ablation efficacy. [Read the Full Post]

Topical Exposure to Nemopilema nomurai Venom Triggers Oedematogenic Effects: Enzymatic Contribution and Identification of Venom Metalloproteinase

313 views | Mar 29 2021

Yang Yue et al. suggested a considerable contribution of NnNV metalloproteinase-like components to the increased vasopermeability. [Read the Full Post]

Betaglycan (TβRIII) is a Key Factor in TGF-β2 Signaling in Prepubertal Rat Sertoli Cells

254 views | Dec 11 2020

Pradeep K Kudipudi et al. found that BG shedding served a major role in TGF-β2 signaling in Sertoli cells. [Read the Full Post]

Protease inhibitors elicit anti-inflammatory effects in CF mice with Pseudomonas aeruginosa acute lung infection

245 views | Dec 11 2020

A Sandri et al. thought that marimastat and Ilomastat represented candidate molecules for the treatment of CF patients, encouraging further studies on protease inhibitors and their application in inflammatory diseases. [Read the Full Post]

An Ilomastat-CD Eye Drop Formulation to Treat Ocular Scarring

371 views | Mar 06 2020

Mohamed-Ahmed AHA et al. showed that Ilomastat-CD has the potential to be formulated as an eye drop for use as an antifibrotic, which may have implications for the prevention of scarring in many settings, for example glaucoma filtration surgery. [Read the Full Post]

Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma

342 views | Dec 04 2019

Ma TT et al suggested a possible novel mechanism that ephrinA1 secretion is mediated by HIF-1α/MMP-2 signaling cascade which may play pivotal roles in OSCC neovascularization in a paracrine manner. [Read the Full Post]