Category

PI3K/Akt/mTOR
- PI3K
- mTOR
- Akt
- GSK-3
- ATM/ATR
- PDK
- S6 Kinase
- AMPK
- DNA-PK
- PTEN
- MELK
- PP2A
- FKBP
- PIKfyve
- PI4K
Epigenetics
- HDAC
- AMPK
- PARP
- JAK
- Pim
- HIF
- PKC
- Aurora Kinase
- Sirtuin
- DNA Methyltransferase
- Histone Demethylase
- Epigenetic Reader Domain
- Histone Acetyltransferase
- Histone Methyltransferase
- JMJD
- PRMT
- EZH1/2
- LSD1
- MicroRNA
- PAD
- SAM MTase
- PPMTase
- WDR5
- SMYD
- COMT
- DOT1
- HNMT
- SETD
- G9a/GLP
- MLL
Methylation
- DNA Methyltransferase
- SAM MTase
- PPMTase
- WDR5
- SMYD
- COMT
- DOT1
- HNMT
- SETD
- G9a/GLP
- MLL
- JMJD
- PRMT
- EZH1/2
- LSD1
Immunology & Inflammation
- CD markers
- PD-1/PD-L1
- COX
- CCR
- Histamine Receptor
- IL Receptor
- ROS
- IDO/TDO
- NADPH-oxidase
- LTR
- MALT
- gp120/CD4
- TLR
- NOS
- Anti-infection
- CXCR
- Nrf2
- NOD
- Immunology & Inflammation related
- Galectin
- MmpL3
- Prostaglandin Receptor
- MIF
- Nur77
- Glutathione
- β-lactamase
- TBK1
- IRAK
- Interleukins
- NLRP3
- SIK
- AKR1C
- TPO
- MyD88
- Heme Oxygenase
- Parasite
- STING
Protein Tyrosine Kinase
- VEGFR
- EGFR
- PDGFR
- c-Met
- HER2
- IGF-1R
- FLT3
- FGFR
- c-Kit
- Src
- ALK
- Tie-2
- c-RET
- BTK
- ACK
- Ephrin receptor
- CSF-1R
- Trk receptor
- Fer kinase
- Pyk2
- ROS1
- Mertk
- Axl
- Tyro3
- DDR
Angiogenesis
- VEGFR
- JAK
- EGFR
- PDGFR
- HER2
- FLT3
- FGFR
- HIF
- VDA
- Bcr-Abl
- Src
- ALK
- Syk
- FAK
- BTK
Apoptosis
- PD-1/PD-L1
- Bcl-2
- Caspase
- p53
- TNF-alpha
- Mdm2
- Survivin
- Ras
- c-RET
- RIP kinase
- PERK
- ASK
- IAP
- Apoptosis related
- OXPHOS
- Heme Oxygenase
- cytohesin
- Bcl-6
- Nur77
- PFKFB
Autophagy
- Autophagy
- CXCR
- LRRK2
- LC3
- ULK
- Mitophagy
- Heme Oxygenase
- OGA
ER stress & UPR
- JNK
- HSP (HSP90)
- PERK
- ASK
- IRE1
- PDI
JAK/STAT
- JAK
- STAT
- EGFR
- Pim
MAPK
- MEK
- Raf
- p38 MAPK
- JNK
- Ras
- KLF
- TAK1
- Mixed Lineage Kinase
- TOPK
- MNK
- ERK
Cytoskeletal Signaling
- Akt
- Wnt/beta-catenin
- Bcr-Abl
- PKC
- FAK
- HSP (HSP90)
- Kinesin
- Microtubule Associated
- Integrin
- MPS1
- PAK
- Dynamin
- Gap-Junction
- PORCN
- TACC3
- MLCK
Cell Cycle
- CDK
- DNA/RNA Synthesis
- PD-1/PD-L1
- Ras
- Aurora Kinase
- Chk
- ROCK
- PLK
- APC
- Wee1
- Rho
- DYRK
- MPS1
- c-Myc
- RUNX
- PFKFB
- LIM kinase
- eIF
- BMI-1
- Choline kinase
- DOCK1
- FOXM1
- Nur77
- TACC3
- PP2A
TGF-beta/Smad
- TGF-beta/Smad
- Bcr-Abl
- PKC
- ROCK
DNA Damage/DNA Repair
- HDAC
- ATM/ATR
- PARP
- DNA/RNA Synthesis
- Sirtuin
- Topoisomerase
- DNA-PK
- Telomerase
- High-mobility Group
- DNA alkylator
- MTH1
- SMN
- Nucleoside Analog/Antimetabolite
- LIM kinase
- eIF
- RAD51
- CRISPR/Cas9
- BMI-1
- G-quadruplex
- RNR
Stem Cells & Wnt
- GSK-3
- JAK
- STAT
- TGF-beta/Smad
- Wnt/beta-catenin
- ROCK
- Gamma-secretase
- Hedgehog/Smoothened
- OCT
- KLF
- Stemness kinase
- Casein Kinase
- Fascin
- PORCN
- Notch
Hippo
- YAP
- MAP4K
- MST
Ubiquitin
- Proteasome
- DUB
- p97
- SUMO
- E2 conjugating
- E1 Activating
- E3 Ligase
Neuronal Signaling
- Beta Amyloid
- 5-HT Receptor
- COX
- Gamma-secretase
- GluR
- Adrenergic Receptor
- AChR
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GABA Receptor
- P-gp
- P2 Receptor
- OX Receptor
- MT Receptor
- GlyT
- NMDAR
- CaMK
- BACE
- Trk receptor
- BChE
- EAAT
- Neurokinin Receptor
- Notch
- CCK receptor
NF-κB
- HDAC
- NF-κB
- IκB/IKK
- NOD
GPCR & G Protein
- 5-HT Receptor
- CCR
- Adrenergic Receptor
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GPR
- Cannabinoid Receptor
- Endothelin Receptor
- S1P Receptor
- Hedgehog/Smoothened
- SGLT
- LPA Receptor
- OX Receptor
- CGRP Receptor
- MT Receptor
- PAFR
- PKA
- CaSR
- CXCR
- Adenosine Receptor
- cAMP
- Vasopressin Receptor
- TAAR
- Glucagon Receptor
- Imidazoline Receptor
- RGS
- Sigma Receptor
- PAR
- GRK
- NPY receptor
- Taste Receptor
- GPCR19
- GHSR
- Guanylate Cyclase
- DOCK1
- CCK receptor
- FPR
- Leukotriene
- Prostaglandin Receptor
- PKD
- Neurokinin Receptor
- PKG
- Angiotensin Receptor
Endocrinology & Hormones
- Adrenergic Receptor
- 5-alpha Reductase
- Estrogen/progestogen Receptor
- Androgen Receptor
- RAAS
- Opioid Receptor
- Aromatase
- GPR
- Glucocorticoid Receptor
- GHSR
- Mineralocorticoid Receptor
- ACE
- THR
- CCK receptor
Transmembrane Transporters
- CD markers
- Calcium Channel
- Sodium Channel
- ATPase
- Chloride Channel
- Potassium Channel
- GABA Receptor
- P-gp
- Proton Pump
- CFTR
- CRM1
- OCT
- MTP
- VMAT
- GlyR
- TRP Channel
- BCRP
- MCT
- Amino acid transporter
- OAT
- OATP
- Aquaporin
- EAAT
- VDAC
Metabolism
- PPAR
- P450 (e.g. CYP17)
- HSP (HSP90)
- PDE
- Hydroxylase
- Factor Xa
- DHFR
- Dehydrogenase
- Procollagen C Proteinase
- Phospholipase (e.g. PLA)
- Carbonic Anhydrase
- Phosphorylase
- MAO
- Liver X Receptor
- FAAH
- Acyltransferase
- AhR
- IDO/TDO
- Ferroptosis
- PKM
- FOX
- Fatty Acid Synthase
- LDL
- Transferase
- GLUT
- phosphatase
- Decarboxylase
- Vitamin
- Thioredoxin
- HMG-CoA Reductase
- Lipoxygenase
- FXR
- Lipase
- NAMPT
- CETP
- Serine/threonin kinase
- Casein Kinase
- Retinoid Receptor
- Glutathione
- Carbohydrate Metabolism
- THR
- PREP
- Xanthine Oxidase
- Peroxidases
- AdipoR
- Aldose Reductase
- PP2A
- OXPHOS
- RUNX
- FABP
- cGAS
- ROR
- SCD
- PGC-1α
- LDH
- PAI-1
- SREBP
- PDHK
- FAO
- CPT
- GTPCH
- GCS
- Epoxide Hydrolase
- FTase
- SGK
- Leukotriene
- Thioredoxin Reductase
- PCSK9
- Mannosidase
- Acetyl-CoA carboxylase
- ACE
- CPSase
- ATP-citrate lyase
Proteases
- Proteasome
- Caspase
- Gamma-secretase
- HCV Protease
- DPP-4
- HIV Protease
- MMP
- Thrombin
- Acyltransferase
- Glutaminase
- Tyrosinase
- Serine Protease
- Cysteine Protease
- SGK
- PREP
- 3C-Like Protease
- PCSK9
Microbiology
- HCV Protease
- Integrase
- Reverse Transcriptase
- HIV Protease
- Anti-infection
- Parasite
- Thioredoxin Reductase
- β-lactamase
- 3C-Like Protease
- COVID-19
- Ribosomal Peptidyl Transferase
Others
- ADC Cytotoxin
- ADC Linker
- Drug-Linker Conjugates for ADC
- Antineoplastic and Immunosuppressive Antibiotics
- Selection Antibiotics for Transfected Cell
- Antibiotics for Mammalian Cell Culture
- Antibiotics for Plant Cell Culture
- Hydrotropic Agents
- Dyes
- PROTAC
- PROTAC Linker
- E3 ligase Ligand
- Target Protein Ligand
- Others

RAAS

Long-term treatment of spontaneously hypertensive rats with PD123319 and electrophysiological remodeling of left ventricular myocardium

287 views | Jan 20 2019

Ying X et al. showed that long-term treatment with PD123319 worsened the development of myocyte hypertrophy and associated electrophysiological alterations in spontaneously hypertensive rat. [Read the Full Post]

Choose Your Country or Region

By Signaling Pathways

By product type

Category

Archives

Popular Post

RAAS

Long-term treatment of spontaneously hypertensive rats with PD123319 and electrophysiological remodeling of left ventricular myocardium