Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis

1246 views | Sep 22 2017

Nie T et al. reveal a new application of harmine in combating obesity via this off-target effect in adipocytes. [Read the Full Post]

Endothelial Cell Apoptosis Induces TGF-b Signaling-Dependent Host Endothelial–Mesenchymal Transition to Promote Transplant Arteriosclerosis

2936 views | Mar 05 2017

Li J et al. suggested that allograft EC apoptosis induced recipient endothelial-mesenchymal (smooth muscle) transition via TGF-β signaling, resulting in recipient EC-derived SMC accumulation as a major mechanism of vascular remodeling during TA. [Read the Full Post]