Angiotensin Receptor

Evolving views on the first two ligands of the angiotensin II type 2 receptor. From putative antagonists to potential agonists?

24 views | Jan 08 2024

The evolving understanding of PD123319's effects challenges its traditional classification as an AT2 receptor antagonist, suggesting potential agonist-like actions at lower doses and highlighting the intricate balance between AT1 and AT2 receptor stimulation within the renin-angiotensin system. [Read the Full Post]

Potential effects and application prospect of angiotensin receptor-neprilysin inhibitor in diabetic kidney disease

317 views | Feb 05 2022

Xingjian Zhang found that ARNI has application potential in DKD, but there still need clinical studies that focus on DKD patients to determine its effectiveness, safety and underlying mechanism. [Read the Full Post]

Hospitalization and Mortality in Patients With Heart Failure Treated With Sacubitril/Valsartan vs. Enalapril: A Real-World, Population-Based Study

557 views | Feb 12 2021

Swathi Pathadka et al. found that in real-world settings, sacubitril/valsartan was associated with improved survival and reduced heart failure-related hospitalization compared to enalapril in Asian patients with heart failure. [Read the Full Post]