Adrenergic Receptor

Signaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1324 Doxazosin Mesylate <1 mg/mL 15 mg/mL <1 mg/mL
S5703 Carvedilol Phosphate -1 mg/mL 100 mg/mL -1 mg/mL
S5723 Carvedilol EP IMpurity E -1 mg/mL 40 mg/mL -1 mg/mL
S5739 Nebivolol -1 mg/mL 88 mg/mL -1 mg/mL
S5088 Labetalone hydrochloride -1 mg/mL 72 mg/mL -1 mg/mL
S4076 Propranolol HCl 6 mg/mL 59 mg/mL <1 mg/mL
S1206 Bisoprolol fumarate 88 mg/mL 88 mg/mL 88 mg/mL
S4113 Desvenlafaxine <1 mg/mL 37 mg/mL 3 mg/mL
S1642 Methyldopa <1 mg/mL 2 mg/mL <1 mg/mL
S4112 Desvenlafaxine Succinate <1 mg/mL 80 mg/mL <1 mg/mL
S2086 Ivabradine HCl 82 mg/mL 101 mg/mL 101 mg/mL
S2113 Cisatracurium Besylate 47 mg/mL 249 mg/mL 249 mg/mL
S1283 Asenapine maleate <1 mg/mL 80 mg/mL <1 mg/mL
S5782 Doxazosin <1 mg/mL 31 mg/mL <1 mg/mL
S5923 Celiprolol hydrochloride -1 mg/mL 83 mg/mL -1 mg/mL
S5778 Esmolol 59 mg/mL 59 mg/mL 59 mg/mL
S5780 Prazosin <1 mg/mL 77 mg/mL <1 mg/mL
S5766 Alfuzosin <1 mg/mL 78 mg/mL 5 mg/mL
S5802 Alprenolol hydrochloride 57 mg/mL 57 mg/mL 57 mg/mL
S5666 Moxisylyte hydrochloride -1 mg/mL 63 mg/mL -1 mg/mL
S9285 Fargesin -1 mg/mL 36 mg/mL -1 mg/mL
s9050 Boldine -1 mg/mL 65 mg/mL -1 mg/mL
S1435 Tamsulosin hydrochloride <1 mg/mL 89 mg/mL <1 mg/mL
S5540 Landiolol hydrochloride 100 mg/mL 100 mg/mL 42 mg/mL
S5341 Metroprolol succinate 100 mg/mL 100 mg/mL 5 mg/mL
S5430 Metoprolol -1 mg/mL 53 mg/mL -1 mg/mL
S5281 Dapiprazole Hydrochloride 72 mg/mL 21 mg/mL 72 mg/mL
S5432 Dibenamine Hydrochloride -1 mg/mL 59 mg/mL -1 mg/mL
S5337 Rauwolscine hydrochloride -1 mg/mL 7 mg/mL -1 mg/mL
S5042 Bevantolol hydrochloride 52 mg/mL 76 mg/mL 61 mg/mL
S4817 Atenolol 35 mg/mL 53 mg/mL 53 mg/mL
S1409 Alfuzosin HCl 85 mg/mL 85 mg/mL 85 mg/mL
S1613 Silodosin <1 mg/mL 99 mg/mL 99 mg/mL
S1549 Nebivolol HCl <1 mg/mL 88 mg/mL <1 mg/mL
S2691 BMY 7378 Dihydrochloride 92 mg/mL 92 mg/mL 20 mg/mL
S1424 Prazosin HCl <1 mg/mL 4 mg/mL <1 mg/mL
S2038 Phentolamine Mesylate 76 mg/mL 76 mg/mL 76 mg/mL
S1856 Metoprolol Tartrate 100 mg/mL 100 mg/mL 31 mg/mL
S2059 Terazosin HCl Dihydrate <1 mg/mL 26 mg/mL <1 mg/mL
S1387 Naftopidil DiHCl <1 mg/mL 41 mg/mL 2 mg/mL
S2517 Maprotiline HCl <1 mg/mL 63 mg/mL 24 mg/mL
S1831 Carvedilol <1 mg/mL 81 mg/mL 4 mg/mL
S2126 Naftopidil <1 mg/mL 79 mg/mL <1 mg/mL
S2499 Phenoxybenzamine HCl 17 mg/mL 68 mg/mL 68 mg/mL
S2509 Sotalol HCl 61 mg/mL 61 mg/mL <1 mg/mL
S4123 Timolol Maleate <1 mg/mL 86 mg/mL 86 mg/mL
S4010 Acebutolol HCl 75 mg/mL 75 mg/mL 75 mg/mL
S1827 Betaxolol HCl 69 mg/mL 69 mg/mL 69 mg/mL
S2607 Buflomedil HCl 69 mg/mL 31 mg/mL 7 mg/mL
S3664 Flupenthixol dihydrochloride 100 mg/mL 100 mg/mL 30 mg/mL
S4124 Tolazoline HCl 39 mg/mL 39 mg/mL 39 mg/mL
S4649 Atipamezole hydrochloride 21 mg/mL 12 mg/mL 49 mg/mL
S4650 Atipamezole <1 mg/mL 42 mg/mL 42 mg/mL
S3656 Piribedil <1 mg/mL 59 mg/mL 59 mg/mL
S4679 Terazosin HCl 1 mg/mL 84 mg/mL <1 mg/mL
S4085 Levobetaxolol HCl 69 mg/mL 69 mg/mL 69 mg/mL
S8114 ICI-118551 Hydrochloride 21 mg/mL 62 mg/mL 62 mg/mL
S4100 Esmolol HCl 66 mg/mL 66 mg/mL 66 mg/mL
S2091 Betaxolol 62 mg/mL 62 mg/mL <1 mg/mL
S4278 Carteolol HCl 65 mg/mL 65 mg/mL <1 mg/mL
S2373 Yohimbine HCl <1 mg/mL 12 mg/mL <1 mg/mL
S4291 Labetalol HCl 8 mg/mL 72 mg/mL 7 mg/mL
S2507 Salbutamol Sulfate 68 mg/mL <1 mg/mL <1 mg/mL
S4009 Mirabegron <1 mg/mL 79 mg/mL 8 mg/mL
S2516 Xylazine HCl 12 mg/mL 50 mg/mL 50 mg/mL
S2083 Procaterol HCl 65 mg/mL 65 mg/mL 3 mg/mL
S5925 Olodaterol hydrochloride 85 mg/mL 85 mg/mL 85 mg/mL
S5669 Isoxsuprine hydrochloride 4 mg/mL 68 mg/mL 4 mg/mL
S5768 Fenoterol hydrobromide 11 mg/mL 77 mg/mL 22 mg/mL
S5769 Fenoterol <1 mg/mL 61 mg/mL 61 mg/mL
S5683 Isoproterenol sulfate dihydrate -1 mg/mL 100 mg/mL -1 mg/mL
S5750 DL-Norepinephrine hydrochloride -1 mg/mL 41 mg/mL -1 mg/mL
S5751 Dihydroergotamine Mesylate -1 mg/mL 100 mg/mL -1 mg/mL
S9507 (−)-Norepinephrine -1 mg/mL 11 mg/mL -1 mg/mL
S9508 Brimonidine -1 mg/mL 26 mg/mL -1 mg/mL
S5564 Xylazine -1 mg/mL 44 mg/mL -1 mg/mL
S5727 Tetryzoline -1 mg/mL 40 mg/mL -1 mg/mL
S5734 Midodrine hydrochloride -1 mg/mL 58 mg/mL -1 mg/mL
S5735 Midodrine -1 mg/mL 51 mg/mL -1 mg/mL
S5217 Arformoterol Tartrate -1 mg/mL 99 mg/mL -1 mg/mL
S5654 Indacaterol <1 mg/mL 52 mg/mL 20 mg/mL
S5267 Nylidrin Hydrochloride 67 mg/mL 2 mg/mL
S5537 Tizanidine 15 mg/mL 50 mg/mL 6 mg/mL
S5494 Salbutamol -1 mg/mL 47 mg/mL -1 mg/mL
S5527 Salmeterol <1 mg/mL 83 mg/mL 83 mg/mL
S3083 Indacaterol Maleate <1 mg/mL 102 mg/mL <1 mg/mL
S2566 Isoprenaline HCl 50 mg/mL 50 mg/mL <1 mg/mL
S2020 Formoterol Hemifumarate <1 mg/mL 80 mg/mL <1 mg/mL
S2521 Epinephrine bitartrate 67 mg/mL 67 mg/mL <1 mg/mL
S2458 Clonidine HCl 53 mg/mL 53 mg/mL 53 mg/mL
S3041 Droxidopa <1 mg/mL <1 mg/mL <1 mg/mL
S3075 Dexmedetomidine <1 mg/mL 40 mg/mL 40 mg/mL
S2522 L-Adrenaline <1 mg/mL 4 mg/mL <1 mg/mL
S2569 Phenylephrine HCl 41 mg/mL 41 mg/mL 41 mg/mL
S4065 Guanabenz Acetate <1 mg/mL 58 mg/mL 5 mg/mL
S2519 Naphazoline HCl 49 mg/mL 17 mg/mL 22 mg/mL
S2533 Ritodrine HCl 65 mg/mL 65 mg/mL 65 mg/mL
S2438 Synephrine HCl 41 mg/mL 14 mg/mL 4 mg/mL
S2090 Dexmedetomidine HCl <1 mg/mL 48 mg/mL 48 mg/mL
S3061 Epinephrine HCl 44 mg/mL 44 mg/mL 7 mg/mL
S3060 Medetomidine HCl 47 mg/mL 12 mg/mL 47 mg/mL
S1437 Tizanidine HCl 15 mg/mL 10 mg/mL <1 mg/mL
S2092 Detomidine HCl 45 mg/mL 45 mg/mL 45 mg/mL
S2545 Scopine <1 mg/mL 31 mg/mL <1 mg/mL
S4296 Salmeterol Xinafoate <1 mg/mL 100 mg/mL 4 mg/mL
S2523 DL-Adrenaline <1 mg/mL 0.02 mg/mL <1 mg/mL
S4266 Brimonidine Tartrate 75 mg/mL 88 mg/mL <1 mg/mL
S3960 Higenamine hydrochloride -1 mg/mL 61 mg/mL -1 mg/mL
S2615 Noradrenaline bitartrate monohydrate 64 mg/mL 64 mg/mL <1 mg/mL
S7974 L755507 <1 mg/mL 100 mg/mL <1 mg/mL
S4127 Terbutaline Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S4135 Clorprenaline HCl 50 mg/mL 50 mg/mL 50 mg/mL
S4043 Tetrahydrozoline HCl 47 mg/mL 12 mg/mL 26 mg/mL
S2576 Xylometazoline HCl 56 mg/mL 27 mg/mL 56 mg/mL
S3640 Methoxyphenamine Hydrochloride 43 mg/mL 43 mg/mL 43 mg/mL
S3643 Amitraz <1 mg/mL 58 mg/mL <1 mg/mL
S3727 Vilanterol Trifenate <1 mg/mL 100 mg/mL 14 mg/mL
S4693 Guanfacine Hydrochloride 30 mg/mL 56 mg/mL 56 mg/mL
S4277 Bambuterol HCl 72 mg/mL 80 mg/mL 28 mg/mL
S2362 Synephrine <1 mg/mL 33 mg/mL 2 mg/mL
S3185 Adrenalone HCl 44 mg/mL 44 mg/mL <1 mg/mL
S4243 Deoxycorticosterone acetate <1 mg/mL 11 mg/mL 6 mg/mL

Isoform-specific Inhibitors

Catalog No. Information Product Use Citations Product Validations

Doxazosin Mesylate

Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.


Carvedilol Phosphate

Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.


Carvedilol EP IMpurity E

Carvedilol is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF).



Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.


Labetalone hydrochloride

Labetalone hydrochloride is hydrochloride form of labetalone, a blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive.


Propranolol HCl

Propranolol HCl is a competitive non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM.


Bisoprolol fumarate

Bisoprolol fumarate is a selective type β1 adrenergic receptor blocker.



Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.



Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.


Desvenlafaxine Succinate

Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.


Ivabradine HCl

Ivabradine HCl, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.


Cisatracurium Besylate

Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.


Asenapine maleate

Asenapine maleate is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.



Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.


Celiprolol hydrochloride

Celiprolol is a β1-adrenoceptor antagonist with partial β2 agonist activity.



Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.



Prazosin is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It is used to treat hypertension.



Alfuzosin, a quinazoline derivative, is a selective and competitive α1-adrenoceptor antagonist.


Alprenolol hydrochloride

Alprenolol hydrochloride is the hydrochloride salt form of alprenolol, which is an beta adrenergic receptorantagonist and is used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.


Moxisylyte hydrochloride

Moxisylyte hydrochloride is an alpha-adrenergic blocking agent used for the treatment of Raynaud's disease.



Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.



Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.


Tamsulosin hydrochloride

Tamsulosin hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.


Landiolol hydrochloride

Landiolol hydrochloride is the hydrochloride salt form of Landiolol, which is an ultra-short-acting β1 selective adrenoceptor antagonist.


Metroprolol succinate

Metoprolol Succinate is the succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity.



Metoprolol is a cardioselective β1-adrenergic blocking agent with log Kd values of −7.26±0.07, −6.89±0.09, −5.16±0.12 for β1, β2, and β3 adrenoceptors, respectively. It is used for acute myocardial infarction, heart failure, angina pectoris and mild to moderate hypertension.


Dapiprazole Hydrochloride

Dapiprazole Hydrochloride is the hydrochloride salt form of dapiprazole, an alpha-adrenergic blocker used to reverse mydriasis after eye examination.


Dibenamine Hydrochloride

Dibenamine is an irreversible blocker of α1 adrenoceptors.


Rauwolscine hydrochloride

Rauwolscine hydrochloride is the hydrochloride salt form of Rauwolscine, a specific and potent α2 antagonist with Ki of 12 nM.


Bevantolol hydrochloride

Bevantolol hydrochloride is a cardioselective, beta adrenoceptor antagonist, devoid of intrinsic β sympathomimetic activity and with weak membrane-stabilizing and local anesthetic properties.



Atenolol is a selective β1 receptor antagonist with log Kd values of −6.66±0.05, −5.99±0.14, −4.11±0.07 for binding to the human β1-, β2- and β3-adrenoceptors.


Alfuzosin HCl

Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).



Silodosin is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.


Nebivolol HCl

Nebivolol HCl selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.


BMY 7378 Dihydrochloride

BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.


Prazosin HCl

Prazosin HCl is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.


Phentolamine Mesylate

Phentolamine Mesylate is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes.


Metoprolol Tartrate

Metoprolol Tartrate is a selective β1 receptor blocker medication, used to treat hypertension and heart failure.


Terazosin HCl Dihydrate

Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).


Naftopidil DiHCl

Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.


Maprotiline HCl

Maprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression.



Carvedilol is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.



Naftopidil is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia.


Phenoxybenzamine HCl

Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.


Sotalol HCl

Sotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.


Timolol Maleate

Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.


Acebutolol HCl

Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.


Betaxolol HCl

Betaxolol is a β1 adrenergic receptor blocker with IC50 of 6 μM.


Buflomedil HCl

Buflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease; A nonselective alpha adrenergic receptor inhibitor.


Flupenthixol dihydrochloride

Flupentixol, an antipsychotic neuroleptic drug, is a powerful antagonist of both D1 and D2 dopamine receptors and also an alpha-adrenergic receptor antagonist.


Tolazoline HCl

Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.


Atipamezole hydrochloride

Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole.



Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.



Piribedil is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties.


Terazosin HCl

Terazosin is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.


Levobetaxolol HCl

Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.


ICI-118551 Hydrochloride

ICI-118551 is a highly selective β2-adrenergic receptor antagonist with Ki values of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.


Esmolol HCl

Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.



Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.


Carteolol HCl

Carteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma.


Yohimbine HCl

Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.


Labetalol HCl

Labetalol HCl is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.


Salbutamol Sulfate

Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.



Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.


Xylazine HCl

Xylazine is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.


Procaterol HCl

Procaterol HCl is a short-acting β2-adrenergic receptor agonist with Kp of 8 nM, used for the treatment of asthma


Olodaterol hydrochloride

Olodaterol hydrochloride is the hydrochloride salt form of Olodaterol, which is a long-acting beta2-adrenergic agonist.


Isoxsuprine hydrochloride

Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity.


Fenoterol hydrobromide

Fenoterol hydrobromide is the the hydrobromide salt of fenoterol, a β2 adrenoreceptor agonist with bronchodilator activity.



Fenoterol is a β2 adrenoreceptor agonist with bronchodilator activity.


Isoproterenol sulfate dihydrate

Isoproterenol Sulfate is the sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity.


DL-Norepinephrine hydrochloride

Norepinephrine is the neurotransmitter at most sympathetic neuroeffector junctions and has pharmacologic effects on both α1 and β1 adrenoceptors.


Dihydroergotamine Mesylate

Dihydroergotamine Mesylate is an ergot derivative with agonistic activity for alpha-adrenergic, serotonergic, and dopaminergic receptors.



(−)-Norepinephrine is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.



Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2) and is used for the treatment of open-angle glaucoma or ocular hypertension to lower intraocular pressure.



Xylazine is a partial alpha-2 adrenergic agonist that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.



Tetryzoline is an alpha-adrenergic agonist used in some over-the-counter eye drops and nasal sprays.


Midodrine hydrochloride

Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor.



Midodrine belongs to the class of medications known as vasopressors. It is an adrenergic alpha-1 agonist.


Arformoterol Tartrate

Arformoterol Tartrate is the tartrate salt of arformoterol, a long-acting beta-2 adrenergic agonist with bronchodilator activity.



Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.


Nylidrin Hydrochloride

Nylidrin Hydrochloride, a β-adrenergic agonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well.



Tizanidine is an imidazoline derivative and a centrally acting α2 adrenergic agonist used as a muscle relaxant for therapy of acute muscle spasms and chronic spasticity.



Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases.



Salmeterol is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT β2AR and shows very high selectivity for the WT β2AR(β1Ki/β2Ki ratio of approximately 1500).


Indacaterol Maleate

Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.


Isoprenaline HCl

Isoprenaline is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block.


Formoterol Hemifumarate

Formoterol Hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).


Epinephrine bitartrate

Epinephrine bitartrate is an alpha- and beta-adrenergic receptor stimulator.


Clonidine HCl

Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.



Droxidopa is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).



Dexmedetomidine is a sedative medication used by intensive care units and anesthetists.



L-Adrenaline belongs to a group of the compounds known as catecholamines.


Phenylephrine HCl

Phenylephrine HCl is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.


Guanabenz Acetate

Guanabenz Acetate is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively.


Naphazoline HCl

Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.


Ritodrine HCl

Ritodrine HCl is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.


Synephrine HCl

SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.


Dexmedetomidine HCl

Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.


Epinephrine HCl

Epinephrine HCl is a hormone and a neurotransmitter.


Medetomidine HCl

Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.


Tizanidine HCl

Tizanidine HCl is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.


Detomidine HCl

Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.



Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.


Salmeterol Xinafoate

Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.



DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands.


Brimonidine Tartrate

Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.


Higenamine hydrochloride

Higenamine, also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants.


Noradrenaline bitartrate monohydrate

Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.



L-755,507 is characterized as a potent and selective β3 adrenergic receptor partial agonist with EC50 of 0.43 nM. It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types.


Terbutaline Sulfate

Terbutaline Sulfate is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.


Clorprenaline HCl

Clorprenaline HCl is a β2-receptor agonist, it has a significant expansion of the bronchial effect.


Tetrahydrozoline HCl

Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity.


Xylometazoline HCl

Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.


Methoxyphenamine Hydrochloride

Methoxyphenamine Hydrochloride is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.



Amitraz is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. It is a non-systemic acaricide and insecticide.


Vilanterol Trifenate

Vilanterol trifenatate is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma.


Guanfacine Hydrochloride

Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect.


Bambuterol HCl

Bambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma.



Synephrine, a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.


Adrenalone HCl

Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.


Deoxycorticosterone acetate

Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.

Tags: adrenergic receptor activation | adrenergic receptor types | adrenergic receptor location | adrenergic receptor drugs | adrenergic receptor signaling | adrenergic receptor pathway | beta adrenergic receptor pathway | beta adrenergic receptor activation | beta 2 adrenergic receptor activation | beta 2 adrenergic receptor pathway | alpha adrenergic receptor pathway | alpha 1 adrenergic receptor pathway | beta 1 adrenergic receptor pathway | adrenergic receptor inhibitor review