Phenoxybenzamine HCl

For research use only.

Catalog No.S2499 Synonyms: NSC 37448, NCI-c01661

Phenoxybenzamine HCl Chemical Structure

CAS No. 63-92-3

Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.

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10mM (1mL in DMSO) USD 130 In stock
USD 97 In stock
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Biological Activity

Description Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
α-adrenergic receptor [1]



Solubility (25°C)

In vitro DMSO 68 mg/mL (199.82 mM)
Water 17 mg/mL (49.95 mM)
Ethanol '68 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 340.3


CAS No. 63-92-3
Storage powder
in solvent
Synonyms NSC 37448, NCI-c01661
Smiles CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01379898 Completed Drug: Phenoxybenzamine|Drug: Doxazosin Pheochromocytoma University Medical Center Groningen|Radboud University|UMC Utrecht|VU University of Amsterdam|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)|Leiden University Medical Center|Erasmus Medical Center|Maastricht University Medical Center|St. Antonius Hospital|Medisch Spectrum Twente|Maxima Medical Center|Canisius-Wilhelmina Hospital|Onze Lieve Vrouwe Gasthuis|Atrium Medical Center|Isala December 2011 Phase 4
NCT00770705 Withdrawn Drug: Phenoxybenzamine|Other: Standard surgical approach Congenital Heart Disease Vanderbilt University|Vanderbilt University Medical Center October 2008 Phase 2

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