Phenoxybenzamine HCl

Catalog No.S2499 Synonyms: NSC 37448, NCI-c01661

Phenoxybenzamine HCl Chemical Structure

Molecular Weight(MW): 340.3

Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.

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Biological Activity

Description Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
Targets
α-adrenergic receptor [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 68 mg/mL (199.82 mM)
Ethanol 68 mg/mL (199.82 mM)
Water 17 mg/mL (49.95 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 340.3
Formula

C18H22ClNO.HCl

CAS No. 63-92-3
Storage powder
in solvent
Synonyms NSC 37448, NCI-c01661

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

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    C4=C3/X C4: LOG(C4):
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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03176693 Recruiting Pheochromocytoma|Paraganglioma University of California Los Angeles May 5 2017 Phase 3
NCT03176693 Recruiting Pheochromocytoma|Paraganglioma University of California Los Angeles May 5 2017 Phase 3
NCT01379898 Completed Pheochromocytoma University Medical Center Groningen|Radboud University|UMC Utrecht|VU University of Amsterdam|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)|Leiden University Medical Center|Erasmus Medical Center|Maastricht University Medical Center|St. Antonius Hospital|Medisch Spectrum Twente|Maxima Medical Center|Canisius-Wilhelmina Hospital|Onze Lieve Vrouwe Gasthuis|Atrium Medical Center|Isala December 2011 Phase 4
NCT01379898 Completed Pheochromocytoma University Medical Center Groningen|Radboud University|UMC Utrecht|VU University of Amsterdam|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)|Leiden University Medical Center|Erasmus Medical Center|Maastricht University Medical Center|St. Antonius Hospital|Medisch Spectrum Twente|Maxima Medical Center|Canisius-Wilhelmina Hospital|Onze Lieve Vrouwe Gasthuis|Atrium Medical Center|Isala December 2011 Phase 4
NCT00770705 Withdrawn Congenital Heart Disease Vanderbilt University|Vanderbilt University Medical Center October 2008 Phase 2
NCT00770705 Withdrawn Congenital Heart Disease Vanderbilt University|Vanderbilt University Medical Center October 2008 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Adrenergic Receptor Signaling Pathway Map

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