Tizanidine HCl

For research use only.

Catalog No.S1437 Synonyms: DS 103-282

Tizanidine HCl Chemical Structure

CAS No. 64461-82-1

Tizanidine HCl (DS 103-282) is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.

Purity & Quality Control

Choose Selective Adrenergic Receptor Inhibitors

Biological Activity

Description Tizanidine HCl (DS 103-282) is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.
Targets
α2-adrenergic receptor [1]

Protocol

References

Solubility (25°C)

In vitro Water 15 mg/mL (51.69 mM)
DMSO 10 mg/mL (34.46 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 290.17
Formula

C9H8ClN5S.HCl

CAS No. 64461-82-1
Storage powder
in solvent
Synonyms DS 103-282
Smiles C1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl.Cl

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01844674 Completed Drug: Tizanidine|Drug: Vemurafenib Malignant Melanoma Neoplasms Hoffmann-La Roche September 2 2013 Phase 1
NCT01839279 Completed Drug: Tizanidine|Drug: Placebo|Drug: Moxifloxacin Spasticity Acorda Therapeutics April 2013 Phase 2
NCT01405950 Terminated Drug: Zanaflex Capsules Spasticity Due to Cerebral Palsy Acorda Therapeutics|Syneos Health May 2011 Phase 1
NCT01065987 Completed Drug: Tizanidine Healthy Dr. Reddy''s Laboratories Limited September 2001 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Adrenergic Receptor Signaling Pathway Map

Related Adrenergic Receptor Products

Tags: buy Tizanidine HCl | Tizanidine HCl ic50 | Tizanidine HCl price | Tizanidine HCl cost | Tizanidine HCl solubility dmso | Tizanidine HCl purchase | Tizanidine HCl manufacturer | Tizanidine HCl research buy | Tizanidine HCl order | Tizanidine HCl mouse | Tizanidine HCl chemical structure | Tizanidine HCl mw | Tizanidine HCl molecular weight | Tizanidine HCl datasheet | Tizanidine HCl supplier | Tizanidine HCl in vitro | Tizanidine HCl cell line | Tizanidine HCl concentration | Tizanidine HCl nmr
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID