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Norepinephrine tartrate Adrenergic Receptor agonist

Name: Norepinephrine tartrate
Brand: Selleck Chemicals
SKU: E2964
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E2964

Norepinephrine tartrate is a potent agonist of adrenergic receptor (AR). Norepinephrine activates α1, α2, β1 receptors.

Norepinephrine tartrate Adrenergic Receptor agonist Chemical Structure

Quality Control

Batch: E296401 DMSO]64 mg/mL]false]Water]64 mg/mL]false]Ethanol]Insoluble]false Purity: 99.55%

Cited in Nature Medicine for its top-tier quality
COA
HPLC
SDS/MSDS
Datasheet

99.55

Related Targets	CXCR Hedgehog/Smoothened PKA AChR 5-HT Receptor Histamine Receptor Dopamine Receptor Ras KRas GPR
Other Adrenergic Receptor Inhibitors	ICI 118551 Hydrochloride (Zenidolol) L755507 Yohimbine HCl Atipamezole Higenamine hydrochloride Noradrenaline bitartrate monohydrate Fenoterol hydrobromide Medetomidine HCl Isoprenaline L-Adrenaline

Solubility

In vitro
Batch:

DMSO : 64 mg/mL (200.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 64 mg/mL

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	319.27	Formula	C₈H₁₁NO₃.C₄H₆O₆	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	3414-63-9	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Read more about storage stability stock solution CAS number

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/17303246/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-05-01)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07562932	NOT_YET_RECRUITING	Cardiogenic Shock	Chonnam National University Hospital	2026-05-31
NCT07363109	NOT_YET_RECRUITING	Hypotension After Spinal Anesthesia; Hypotension During Cesarean Delivery	Aretaieion University Hospital	2026-02
NCT07063680	RECRUITING	Patients With Norepinephrine-refractory Vasoplegic Shock	Centre Hospitalier Universitaire Dijon	2026-04-07	PHASE3
NCT07667829	NOT_YET_RECRUITING	Pulmonary Arterial Hypertension (PAH); Chronic Thromboembolic Pulmonary Hypertension (CTEPH); Hypertension, Pulmonary	China National Center for Cardiovascular Diseases	2026-06
NCT06746753	NOT_YET_RECRUITING	Septic Shock	Wake Forest University Health Sciences	2026-09	PHASE4
NCT06802224	RECRUITING	Anesthesia; Surgery With General Anesthesia; Noncardiac Surgery; Hypotension During Surgery; Acute Kidney Injury (AKI); Myocardial Injury After Noncardiac Surgery (MINS); Vasopressor	University of California, San Francisco	2025-04-01	PHASE4

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