Indacaterol

Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.

Indacaterol Chemical Structure

Indacaterol Chemical Structure

CAS: 312753-06-3

Selleck's Indacaterol has been cited by 2 publications

Purity & Quality Control

Batch: Purity: 99.99%
99.99

Indacaterol Related Products

Choose Selective Adrenergic Receptor Inhibitors

Biological Activity

Description Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.
Targets
β1-adrenoceptor [1]
(Cell-fee assay)
β2-adrenoceptor [1]
(Cell-free assay)
7.36(pKi) 5.48(pKi)
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05288075 Completed
Healthy Volunteers
Orion Corporation Orion Pharma
February 28 2022 Phase 1
NCT03030638 Completed
Pulmonary Disease Chronic Obstructive
Boehringer Ingelheim|RTI health solutions US
February 8 2017 --

Chemical Information & Solubility

Molecular Weight 392.49 Formula

C24H28N2O3

CAS No. 312753-06-3 SDF --
Smiles CCC1=C(C=C2CC(CC2=C1)NCC(C3=C4C=CC(=O)NC4=C(C=C3)O)O)CC
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 52 mg/mL ( (132.48 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 20 mg/mL

Water : Insoluble


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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