Home Neuronal Signaling Adrenergic Receptor antagonist (R)-tamsulosin For research use only.

(R)-tamsulosin

Synonyms: (R)-(-)-YM12617 free base, LY253351 free base

(R)-Tamsulosin ((R)-(-)-YM12617 free base, LY253351 free base) is the enantiomerically pure, pharmacologically active form of tamsulosin, a selective α₁A-adrenergic receptor antagonist used in the treatment of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). This form is synthesized using chiral N-(1-phenylethyl)aziridine-2-carboxylate derivatives, which allow for highly stereoselective processes in its production.

(R)-tamsulosin Chemical Structure

(R)-tamsulosin Chemical Structure

CAS No. 106133-20-4

Purity & Quality Control

Batch: E605601 DMSO]82 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.84%
99.84

(R)-tamsulosin Related Products

Signaling Pathway

Adrenergic Receptor Signaling Pathways

Adrenergic Receptor Signaling Pathway

Biological Activity

Description (R)-Tamsulosin ((R)-(-)-YM12617 free base, LY253351 free base) is the enantiomerically pure, pharmacologically active form of tamsulosin, a selective α₁A-adrenergic receptor antagonist used in the treatment of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). This form is synthesized using chiral N-(1-phenylethyl)aziridine-2-carboxylate derivatives, which allow for highly stereoselective processes in its production.

Chemical Information & Solubility

Molecular Weight 408.51 Formula

C20H28N2O5S
CAS No. 106133-20-4 SDF Download (R)-tamsulosin SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 82 mg/mL ( (200.72 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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