Midodrine hydrochloride

For research use only.

Catalog No.S5734

Midodrine hydrochloride Chemical Structure

Molecular Weight(MW): 290.74

Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor.

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Biological Activity

Description Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor.



Solubility (25°C)

In vitro DMSO 58 mg/mL (199.49 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 290.74


CAS No. 43218-56-0
Storage powder
in solvent
Synonyms N/A
Smiles COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04455464 Recruiting Drug: Midodrine Oral Tablet Chronic Liver Disease Institute of Liver and Biliary Sciences India July 11 2020 Not Applicable
NCT03856151 Recruiting Device: HEALTHY BOX Powered heating pad Hemodialysis-Induced Symptom|Intra-dialytic Hypotension Chang Gung Memorial Hospital April 17 2019 Not Applicable
NCT03911817 Completed Drug: Midodrine Septic Shock Ain Shams University November 15 2017 Phase 4
NCT02771158 Withdrawn Drug: Midodrine|Drug: placebo Hypotension|Shock Septic|Sepsis Northwell Health August 2017 Phase 4
NCT02383121 Withdrawn Drug: Midodrine Stroke University of Utah May 10 2017 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID