Dexmedetomidine HCl

For research use only.

Catalog No.S2090

1 publication

Dexmedetomidine HCl  Chemical Structure

CAS No. 145108-58-3

Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 140 In stock
USD 79 In stock
USD 227 In stock
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Selleck's Dexmedetomidine HCl has been cited by 1 publication

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Biological Activity

Description Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
alpha-2 adrenoceptor [1]


Solubility (25°C)

In vitro DMSO 48 mg/mL (202.75 mM)
Ethanol 48 mg/mL (202.75 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 236.74


CAS No. 145108-58-3
Storage powder
in solvent
Synonyms N/A
Smiles CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04730609 Not yet recruiting Drug: Dexmedetomidine Shivering|Dose Finding Study Mayo Clinic June 2021 Phase 4
NCT04027829 Completed Drug: Dexmedetomidine Hydrochloride Intensive Care Unit|Postoperative Care Seoul National University Hospital|Ministry of Food and Drug Safety Korea August 14 2019 Phase 2
NCT03762785 Unknown status Drug: nebulized Dexmedetomidine Abdominal Cancer Assiut University December 10 2018 Phase 1|Phase 2
NCT03597477 Completed Drug: Dexmedetomidine Autism Spectrum Disorder Guangzhou Women and Children''s Medical Center July 16 2018 --
NCT03417999 Recruiting Drug: Dexmedetomidine Dexmedetomidine|Congenital Heart Disease Children''s Hospital of Philadelphia June 1 2018 Phase 1
NCT03466242 Unknown status Drug: Dexmedetomidine|Drug: Ketamine Conscious Sedation|Distal Radius Fracture Phoenix Children''s Hospital May 1 2018 Early Phase 1

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