Dexmedetomidine HCl

Synonyms: (+)-Medetomidine Hydrochloride

Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.

Dexmedetomidine HCl  Chemical Structure

Dexmedetomidine HCl Chemical Structure

CAS No. 145108-58-3

Purity & Quality Control

Batch: S209001 DMSO]48 mg/mL]false]Ethanol]48 mg/mL]false]Water]20 mg/mL]false Purity: 99.98%
99.98

Dexmedetomidine HCl Related Products

Biological Activity

Description Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
Targets
alpha-2 adrenoceptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05342376 Unknown status
Postoperative Shivering|Cesarean Delivery
Rehman Medical Institute - RMI
February 1 2022 Phase 4

Chemical Information & Solubility

Molecular Weight 236.74 Formula

C13H16N2.HCl

CAS No. 145108-58-3 SDF Download Dexmedetomidine HCl SDF
Smiles CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 48 mg/mL ( (202.75 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 48 mg/mL

Water : 20 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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