Dexmedetomidine HCl

Catalog No.S2090

For research use only.

Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.

Dexmedetomidine HCl  Chemical Structure

CAS No. 145108-58-3

Selleck's Dexmedetomidine HCl has been cited by 2 Publications

Purity & Quality Control

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Biological Activity

Description Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
Targets
alpha-2 adrenoceptor [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 236.74
Formula

C13H16N2.HCl

CAS No. 145108-58-3
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04513314 Not yet recruiting Drug: Valproate|Drug: Quetiapine|Other: Standard of Care Covid19|Hyperactive Delirium|Pneumonia Viral University of Miami November 1 2022 Phase 4
NCT05065775 Not yet recruiting Device: Dexmedetomidine Pharmacokinetics|Arthritis Knee|Arthritis of Hip|Anesthesia Turku University Hospital November 1 2021 Phase 4
NCT05072704 Not yet recruiting Drug: Sufentanil|Drug: Dexmedetomidine Primary Total Hip Arthroplasty CMC Ambroise Paré November 1 2021 Phase 3
NCT04973124 Not yet recruiting Drug: Dexmedetomidine|Drug: Placebo Anesthesia|Dexmedetomidine|Aging Pontificia Universidad Catolica de Chile October 20 2021 Not Applicable
NCT04730609 Recruiting Drug: Dexmedetomidine Shivering|Dose Finding Study Mayo Clinic September 21 2021 Phase 4

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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