Nebivolol

Catalog No.S5739 Synonyms: Bystolic

Nebivolol Chemical Structure

Molecular Weight(MW): 405.43

Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.

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Biological Activity

Description Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.

Protocol

References

Solubility (25°C)

In vitro DMSO 88 mg/mL (217.05 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 405.43
Formula

C22H25F2NO4

CAS No. 118457-14-0
Storage powder
in solvent
Synonyms Bystolic

Bio Calculators

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03847350 Completed -- Essential Hypertension A.Menarini Asia-Pacific Holdings Pte Ltd July 1 2015 --
NCT01885988 Unknown status Drug: Nebivolol|Drug: Sugar Pill Erectile Dysfunction Martin M. Miner MD|Forest Laboratories|The Miriam Hospital March 2013 Phase 4
NCT01522950 Completed Drug: Nebivolol|Drug: atenolol|Drug: placebo Hypertension University of Minnesota - Clinical and Translational Science Institute|Forest Laboratories May 2010 Phase 2
NCT01057251 Completed Drug: Nebivolol|Drug: Placebo Hypertension Forest Laboratories March 2010 Phase 4
NCT01077661 Completed Drug: Nebivolol Hypertension|Heart Failure GlaxoSmithKline October 2009 --

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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